ChemSpider 2D Image | amentoflavone | C30H18O10

amentoflavone

  • Molecular FormulaC30H18O10
  • Average mass538.458 Da
  • Monoisotopic mass538.090027 Da
  • ChemSpider ID4444919

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1617-53-4 [RN]
3,8''-Biapigenin
4H-1-Benzopyran-4-one, 8-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-
4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)
4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)- [ACD/Index Name]
8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-on [German] [ACD/IUPAC Name]
8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one [ACD/IUPAC Name]
8-[5-(5,7-Dihydroxy-4-oxo-4H-chromén-2-yl)-2-hydroxyphényl]-5,7-dihydroxy-2-(4-hydroxyphényl)-4H-chromén-4-one [French] [ACD/IUPAC Name]
9I1VC79L77
amentoflavone [Wiki]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

40584_FLUKA [DBID]
AIDS000485 [DBID]
AIDS-000485 [DBID]
C10018 [DBID]
MLS000574827 [DBID]
NSC 295677 [DBID]
NSC295677 [DBID]
SMR000156235 [DBID]
  • Spectroscopy
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring. A natural product f ound particularly in <ital>Ginkgo biloba</ital> and <ital>Hypericum perforatum</ital>. ChEBI CHEBI:2631
      A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring. A natural product f ound particularly in Ginkgo biloba and Hypericum perforatum. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:2631, CHEBI:2631

    • Compound Source:

      Isolated from a plant Susan Richardson [Structure found on ChemSpider, confirmed from ACD/Dictionary, ChEBI, ChEMBL and DOI: 10.1590/S0102-695X2007000300003]
      Ouratea multiflora (Ochnaceae) Susan Richardson [Structure found on ChemSpider, confirmed from ACD/Dictionary, ChEBI, ChEMBL and DOI: 10.1590/S0102-695X2007000300003]

    • Bio Activity:

      Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects.; IC50 value:; Target:; In vitro: In irradiated v79 cells, Pretreatment with amentoflavone 24 hours prior to 8 Gy 60Co ?-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass [2]. MedChem Express HY-N0662
      Others MedChem Express HY-N0662

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.7±0.1 g/cm3
Boiling Point: 910.5±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±0.3 mmHg at 25°C
Enthalpy of Vaporization: 136.9±3.0 kJ/mol
Flash Point: 308.5±27.8 °C
Index of Refraction: 1.793
Molar Refractivity: 138.0±0.3 cm3
#H bond acceptors: 10
#H bond donors: 6
#Freely Rotating Bonds: 3
#Rule of 5 Violations: 3
ACD/LogP: 3.11
ACD/LogD (pH 5.5): 3.38
ACD/BCF (pH 5.5): 189.00
ACD/KOC (pH 5.5): 1239.63
ACD/LogD (pH 7.4): 0.38
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.23
Polar Surface Area: 174 Å2
Polarizability: 54.7±0.5 10-24cm3
Surface Tension: 93.1±3.0 dyne/cm
Molar Volume: 325.0±3.0 cm3

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