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ChemSpider 2D Image | dihydroergotamine | C33H37N5O5


  • Molecular FormulaC33H37N5O5
  • Average mass583.677 Da
  • Monoisotopic mass583.279480 Da
  • ChemSpider ID10091
  • defined stereocentres - 7 of 7 defined stereocentres

More details:

Featured data source

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(5'α,10α)-5'-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman [ACD/IUPAC Name]
(5'α,10α)-5'-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman [German] [ACD/IUPAC Name]
(5'α,10α)-5'-Benzyl-12'-hydroxy-2'-méthyl-3',6',18-trioxo-9,10-dihydroergotaman [French] [ACD/IUPAC Name]
208-123-3 [EINECS]
511-12-6 [RN]
dihidroergotamina [Spanish] [INN]
dihydroergotamine [INN] [Wiki]
dihydroergotamine [French] [INN]

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

436O5HM03C [DBID]
BRN 5720196 [DBID]
C07798 [DBID]
DivK1c_000592 [DBID]
KBio1_000592 [DBID]
KBio2_001537 [DBID]
KBio2_004105 [DBID]
KBio2_006673 [DBID]
KBio3_001429 [DBID]
  • Miscellaneous
    • Toxicity:

      Organic Compound; Amine; Ether; Amide; Drug; Analgesic, Non-Narcotic; Sympatholytic; Vasoconstrictor Agent; Analgesic; Anti-Migraine Agent; Dopamine Agonist; Metabolite; Synthetic Compound Toxin, Toxin-Target Database T3D2750
    • Safety:

      N02CA01 Wikidata Q421336
    • Chemical Class:

      Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (a s the methanesulfonic or tartaric acid salts) for the treatment of migraine and orthostatic hypotension. ChEBI CHEBI:4562,

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.5±0.1 g/cm3
Boiling Point: 899.5±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±0.3 mmHg at 25°C
Enthalpy of Vaporization: 137.0±3.0 kJ/mol
Flash Point: 497.8±34.3 °C
Index of Refraction: 1.727
Molar Refractivity: 159.5±0.4 cm3
#H bond acceptors: 10
#H bond donors: 3
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 2
ACD/LogP: 3.53
ACD/LogD (pH 5.5): 1.03
ACD/BCF (pH 5.5): 1.30
ACD/KOC (pH 5.5): 12.83
ACD/LogD (pH 7.4): 2.57
ACD/BCF (pH 7.4): 45.34
ACD/KOC (pH 7.4): 447.07
Polar Surface Area: 118 Å2
Polarizability: 63.2±0.5 10-24cm3
Surface Tension: 79.9±5.0 dyne/cm
Molar Volume: 400.8±5.0 cm3

Click to predict properties on the Chemicalize site