ChemSpider 2D Image | Decamethonium Bromide | C16H38Br2N2

Decamethonium Bromide

  • Molecular FormulaC16H38Br2N2
  • Average mass418.294 Da
  • Monoisotopic mass416.140167 Da
  • ChemSpider ID10459
  • Charge - Charge


More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1,10-Decanediaminium, N,N,N,N',N',N'-hexamethyl-, dibromide
1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2) [ACD/Index Name]
208-772-2 [EINECS]
541-22-0 [RN]
Decamethonium Bromide [INN]
Decamethonium dibromide
Decamethylene bis(trimethylammonium bromide)
decamethylenebis[trimethylammonium bromide]
Dibromure de N,N,N,N',N',N'-hexaméthyl-1,10-décanediaminium [French] [ACD/IUPAC Name]
MFCD00011779
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

C 10 [DBID]
30518_FLUKA [DBID]
D1260_SIGMA [DBID]
EU-0100385 [DBID]
HL 8562 [DBID]
NSC 23004 [DBID]
UNII:55C6RK944K [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Appearance:

      crystalline solid Oxford University Chemical Safety Data (No longer updated) More details
    • Stability:

      Stable. Incompatible with strong oxidizing agents. Oxford University Chemical Safety Data (No longer updated) More details
    • Toxicity:

      IPR-RAT LD50 2.9 mg kg-1 Oxford University Chemical Safety Data (No longer updated) More details
    • Safety:

      Safety glasses, gloves, good ventilation. Oxford University Chemical Safety Data (No longer updated) More details
    • Target Organs:

      AChE inhibitor;AChR agonist TargetMol T0818
    • Bio Activity:

      AChE; Neuronal AChR TargetMol T0818
      Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent. MedChem Express
      Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.; Target: nAChR; Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. MedChem Express HY-B0570
      Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.;Target: nAChRDecamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle. In the process of binding, decamethonium actually activates (depolarizes) the motor endplate, but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release [1]. MedChem Express HY-B0570
      Membrane Tranporter/Ion Channel MedChem Express HY-B0570
      Membrane Tranporter/Ion Channel; Neuronal Signaling; MedChem Express HY-B0570
      nAChR MedChem Express HY-B0570
      Neuroscience TargetMol T0818

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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