ChemSpider 2D Image | LZ5776539 | C36H62O8

LZ5776539

  • Molecular FormulaC36H62O8
  • Average mass622.873 Da
  • Monoisotopic mass622.444458 Da
  • ChemSpider ID106568

  • defined stereocentres - 15 of 15 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(20S)-ginsenoside Rh2
(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside [ACD/IUPAC Name]
(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranosid [German] [ACD/IUPAC Name]
(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside
20(S)-Ginsenoside Rh2
20(S)-Ginsenoside-RH2
78214-33-2 [RN]
ginsenoside Rh2
LZ5776539
MFCD00800712
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      EGFR inhibitor TargetMol T2959

    • Chemical Class:

      A ginsenoside found in <ital>Panax</ital> species that is dammarane which is substituted by hydroxy groups at the 3<stereo>beta</stereo>, 12<stereo>beta</stereo> and 20 <ital>pro</ital>-<stereo>S</ste reo> positions, in which the hydroxy group at position 3 has been converted to the corresponding <stereo>beta</stereo>-<stereo>D</stereo>-glucopyranoside, and in which a double bond has been introduce d at the 24-25 position. ChEBI CHEBI:77147
      A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted t o the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:77147, CHEBI:77147

    • Compound Source:

      ginsenoside degradation III PlantCyc CPD-12104
      Linum usitatissimum PlantCyc CPD-12104

    • Bio Activity:

      (20S)-ginsenoside Rg3 + H2O -> (20S)-ginsenoside Rh2 + D-glucopyranose PlantCyc CPD-12104
      EGFR TargetMol T2959
      Ginsenoside Rh2, an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug. MedChem Express
      Ginsenoside Rh2, an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.; IC50 value:; Target:; In vitro: Ginsenoside Rh2 inhibited the growth of cultured human UL cells in vitro. MedChem Express HY-N0605
      Others MedChem Express HY-N0605
      Tyrosine Kinase/Adaptors TargetMol T2959

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 726.4±60.0 °C at 760 mmHg
Vapour Pressure: 0.0±5.4 mmHg at 25°C
Enthalpy of Vaporization: 121.1±6.0 kJ/mol
Flash Point: 393.1±32.9 °C
Index of Refraction: 1.572
Molar Refractivity: 170.7±0.4 cm3
#H bond acceptors: 8
#H bond donors: 6
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 3
ACD/LogP: 5.62
ACD/LogD (pH 5.5): 4.92
ACD/BCF (pH 5.5): 3243.93
ACD/KOC (pH 5.5): 11345.38
ACD/LogD (pH 7.4): 4.92
ACD/BCF (pH 7.4): 3243.91
ACD/KOC (pH 7.4): 11345.31
Polar Surface Area: 140 Å2
Polarizability: 67.7±0.5 10-24cm3
Surface Tension: 54.5±5.0 dyne/cm
Molar Volume: 519.1±5.0 cm3

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