ChemSpider 2D Image | 5-Amino-4-oxopentansäurehydrochlorid | C5H10ClNO3

5-Amino-4-oxopentansäurehydrochlorid

  • Molecular FormulaC5H10ClNO3
  • Average mass167.591 Da
  • Monoisotopic mass167.034927 Da
  • ChemSpider ID110200

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5-amino-4-oxopentanoic acid hydrochloride
5-Amino-4-oxopentanoic acid hydrochloride (1:1) [ACD/IUPAC Name]
5-Amino-4-oxopentansäurehydrochlorid
5-Amino-4-oxopentansäurehydrochlorid (1:1) [German] [ACD/IUPAC Name]
5-Amino-4-oxo-valeric acid hydrochloride [ACD/IUPAC Name]
5-Aminolaevulinic acid hydrochloride
5-Aminolevulinic acid hydrochloride
acide 5-amino-4-oxopentanoïque chlorhydrate
Acide 5-amino-4-oxopentanoïque, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
Levulinic acid, 5-amino-, hydrochloride
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

V35KBM8JGR [DBID]
02.09.5451 [DBID]
08339_FLUKA [DBID]
08340_FLUKA [DBID]
A3785_SIGMA [DBID]
A7793_SIGMA [DBID]
CCRIS 4693 [DBID]
D02908 [DBID]
NSC 18509 [DBID]
UNII:V35KBM8JGR [DBID]
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      CAUTION: May irritate eyes, skin, and respiratory tract Alfa Aesar A16942

    • Target Organs:

      Amino Acids and Derivatives TargetMol T1662

    • Chemical Class:

      A hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue ligh t illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:132969, CHEBI:132969

    • Bio Activity:

      5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. MedChem Express
      5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.; Target: Others; 5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of these tumours. MedChem Express HY-N0305
      5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.;Target: 5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of these tumours. Median follow-up was 35.4 months (95% CI 1.0-56.7). Contrast-enhancing tumour was resected completely in 90 (65%) of 139 patients assigned 5-aminolevulinic acid compared with 47 (36%) of 131 assigned white light (difference between groups 29% [95% CI 17-40], p<0.0001). Patients allocated 5-aminolevulinic acid had higher 6-month progression free survival than did those allocated white light (41.0% [32.8-49.2] vs 21.1% [14.0-28.2]; difference between groups 19.9% [9.1-30.7], p=0.0003, Z test) [1]. 5-ALA alone proved to be insufficient in attaining gross total resection without the danger of incurring postopera MedChem Express HY-N0305
      Amino Acids & Building Blocks TargetMol T1662
      Aminolevulinic acid dehydratase TargetMol T1662
      Biochemicals and Molecular Biology Tocris Bioscience 5514
      Others MedChem Express HY-N0305
      Reagents Tocris Bioscience 5514
      Substrate for detection of ?-aminolevulinic acid dehydratase Tocris Bioscience 5514
      Substrate for detection of ?-aminolevulinic acid dehydratase. Used in fluorescence guided resection of tumors. Tocris Bioscience 5514
      Substrate for detection of delta-aminolevulinic acid dehydratase Tocris Bioscience 5514
      Substrate for detection of delta-aminolevulinic acid dehydratase. Used in fluorescence guided resection of tumors. Tocris Bioscience 5514

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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