ChemSpider 2D Image | Y-320 | C27H29ClN6O2


  • Molecular FormulaC27H29ClN6O2
  • Average mass505.011 Da
  • Monoisotopic mass504.204041 Da
  • ChemSpider ID11239888

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-(4-Chlorophenyl)-N-{3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl}-5-methyl-1H-pyrazole-4-carboxamide [ACD/IUPAC Name]
1-(4-Chlorophényl)-N-{3-cyano-4-[4-(4-morpholinyl)-1-pipéridinyl]phényl}-5-méthyl-1H-pyrazole-4-carboxamide [French] [ACD/IUPAC Name]
1-(4-Chlorphenyl)-N-{3-cyan-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl}-5-methyl-1H-pyrazol-4-carboxamid [German] [ACD/IUPAC Name]
1H-Pyrazole-4-carboxamide, 1-(4-chlorophenyl)-N-[3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-5-methyl- [ACD/Index Name]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Target Organs:

      ATGL inhibitor TargetMol T1846
    • Bio Activity:

      ATGL TargetMol T1846
      Immunology/Inflammation; MedChem Express HY-15898
      Interleukin Related MedChem Express HY-15898
      Metabolism TargetMol T1846
      Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. MedChem Express

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.3±0.1 g/cm3
Boiling Point: 631.2±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.8 mmHg at 25°C
Enthalpy of Vaporization: 93.3±3.0 kJ/mol
Flash Point: 335.6±31.5 °C
Index of Refraction: 1.675
Molar Refractivity: 140.8±0.5 cm3
#H bond acceptors: 8
#H bond donors: 1
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 3.58
ACD/LogD (pH 5.5): 1.69
ACD/BCF (pH 5.5): 3.74
ACD/KOC (pH 5.5): 23.91
ACD/LogD (pH 7.4): 3.33
ACD/BCF (pH 7.4): 162.13
ACD/KOC (pH 7.4): 1035.47
Polar Surface Area: 86 Å2
Polarizability: 55.8±0.5 10-24cm3
Surface Tension: 54.4±7.0 dyne/cm
Molar Volume: 374.9±7.0 cm3

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