ChemSpider 2D Image | Bazedoxifene Acetate | C32H38N2O5

Bazedoxifene Acetate

  • Molecular FormulaC32H38N2O5
  • Average mass530.654 Da
  • Monoisotopic mass530.278076 Da
  • ChemSpider ID135920

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-{4-[2-(1-Azepanyl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate (1:1) [ACD/IUPAC Name]
1-{4-[2-(1-Azepanyl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-olacetat (1:1) [German] [ACD/IUPAC Name]
1-{4-[2-(Azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate (1:1)
198481-33-3 [RN]
1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-, acetate (1:1) (salt) [ACD/Index Name]
Acide acétique - 1-{4-[2-(1-azépanyl)éthoxy]benzyl}-2-(4-hydroxyphényl)-3-méthyl-1H-indol-5-ol (1:1) [French] [ACD/IUPAC Name]
Bazedoxifene Acetate [USAN]
J70472UD3D
[198481-33-3]
1-({4-[2-(AZEPAN-1-YL)ETHOXY]PHENYL}METHYL)-2-(4-HYDROXYPHENYL)-3-METHYL-1H-INDOL-5-OL; ACETIC ACID
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

WAY-140424 [DBID]
CCRIS 4693 [DBID]
D03062 [DBID]
TSE-424 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      5 Axon Medchem 2051
      H303;H313;H317;H333;H334;H335;H373 Axon Medchem 2051
      no pictogram Axon Medchem 2051
      P101;P102;P103;P260;P262;P263;P264;P270;P280;P304;P312;P340 Axon Medchem 2051
      Sold for research purposes under agreement from Pfizer Inc. Tocris Bioscience 5263
      Warning Axon Medchem 2051
    • Target Organs:

      Estrogen/Progestogen Receptor modulator TargetMol T2544
    • Bio Activity:

      Bazedoxifene acetate (TSE 424; WAY-TES 424), a novel selective estrogen receptor modulator (SERM), has been developed to have favorable effects on bone and the lipid profile while minimizing stimulati on of uterine or breast tissues. MedChem Express http://www.medchemexpress.com/cilazapril.html
      Bazedoxifene acetate (TSE 424; WAY-TES 424), a novel selective estrogen receptor modulator (SERM), has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. MedChem Express HY-A0036
      Bazedoxifene acetate (TSE 424; WAY-TES 424), a novel selective estrogen receptor modulator (SERM), has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. ;IC50 value:;Target: SERM;Two large Phase III clinical trials showed that Bazedoxifene, as well as raloxifene, increased bone mineral density, decreased levels of bone turnover markers, and significantly reduced the risk of new vertebral fractures in postmenopausal women compared with placebo. MedChem Express HY-A0036
      Endocrinology/ Hormones TargetMol T2544
      Er??;Er?? TargetMol T2544
      Estrogen and Related Receptors Tocris Bioscience 5263
      Estrogen Receptor/ERR MedChem Express HY-A0036
      Nuclear Receptors Tocris Bioscience 5263
      Others MedChem Express HY-A0036
      Potent and selective estrogen receptor modulator (SERM) Tocris Bioscience 5263
      Potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99 nM for ER? and ER? respectively). Inhibits 17?-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxife ne (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium. Tocris Bioscience 5263
      Potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99 nM for ER? and ER? respectively). Inhibits 17?-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium. Tocris Bioscience 5263
      Potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99 nM for ERalpha and ERbeta respectively). Inhibits 17beta-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium. Tocris Bioscience 5263

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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