ChemSpider 2D Image | Paromomycin | C23H45N5O14


  • Molecular FormulaC23H45N5O14
  • Average mass615.628 Da
  • Monoisotopic mass615.296326 Da
  • ChemSpider ID145115
  • defined stereocentres - 19 of 19 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside [ACD/IUPAC Name]
(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-didesoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl-2-amino-2-desoxy-α-D-glucopyranosid [German] [ACD/IUPAC Name]
1263-89-4 [RN]
231-423-0 [EINECS]
2-Amino-2-désoxy-α-D-glucopyranoside de (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-didésoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyle [French] [ACD/IUPAC Name]
4-18-00-07534 [Beilstein]

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

R 400 [DBID]
AIDS005084 [DBID]
AIDS-005084 [DBID]
AIDS081129 [DBID]
AIDS-081129 [DBID]
BRN 0072285 [DBID]
C00832 [DBID]
  • Miscellaneous
    • Safety:

      A07AA06 Wikidata Q415625
    • Chemical Class:

      An amino cyclitol glycoside that is the 1-<element>O</element>-(2-amino-2-deoxy-<stereo>alpha</stereo>-<stereo>D</stereo>-glucopyranoside) and the 3-<element>O</element>-(2,6-diamino-2,6-dideoxy-<ster eo>beta</stereo>-<stereo>L</stereo>-idopyranosyl)-<stereo>beta</stereo>-<stereo>D</stereo>-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1<stereo>R</stereo>,2<stereo>R</stereo>,3<stereo> S</stereo>,4<stereo>R</stereo>,6<stereo>S</stereo> diastereoisomer). It is obtained from various <ital>Streptomyces</ital> species. A broad-spectrum antibiotic, it is used (generally as the sulfate sa lt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmanias is. ChEBI CHEBI:7934

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.6±0.1 g/cm3
Boiling Point: 939.8±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±0.6 mmHg at 25°C
Enthalpy of Vaporization: 155.1±6.0 kJ/mol
Flash Point: 522.2±34.3 °C
Index of Refraction: 1.676
Molar Refractivity: 140.8±0.4 cm3
#H bond acceptors: 19
#H bond donors: 18
#Freely Rotating Bonds: 9
#Rule of 5 Violations: 3
ACD/LogP: -3.27
ACD/LogD (pH 5.5): -11.48
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -9.85
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 347 Å2
Polarizability: 55.8±0.5 10-24cm3
Surface Tension: 106.4±5.0 dyne/cm
Molar Volume: 374.1±5.0 cm3

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