ChemSpider 2D Image | Paromomycin | C23H45N5O14

Paromomycin

  • Molecular FormulaC23H45N5O14
  • Average mass615.628 Da
  • Monoisotopic mass615.296326 Da
  • ChemSpider ID145115

  • defined stereocentres - 19 of 19 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside [ACD/IUPAC Name]
(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-didesoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl-2-amino-2-desoxy-α-D-glucopyranosid [German] [ACD/IUPAC Name]
1263-89-4 [RN]
231-423-0 [EINECS]
2-Amino-2-désoxy-α-D-glucopyranoside de (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-didésoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]oxy}-3-hydroxycyclohexyle [French] [ACD/IUPAC Name]
4-18-00-07534 [Beilstein]
Aminosidine
Amminosidin
Antibiotic 2230D
Antibiotic 503-3
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

61JJC8N5ZK [DBID]
939 [DBID]
R 400 [DBID]
AIDS005084 [DBID]
AIDS-005084 [DBID]
AIDS081129 [DBID]
AIDS-081129 [DBID]
BRN 0072285 [DBID]
C00832 [DBID]
UNII:61JJC8N5ZK [DBID]
More...
  • Miscellaneous

    • Safety:

      A07AA06 Wikidata Q415625

    • Chemical Class:

      An amino cyclitol glycoside that is the 1-<element>O</element>-(2-amino-2-deoxy-<stereo>alpha</stereo>-<stereo>D</stereo>-glucopyranoside) and the 3-<element>O</element>-(2,6-diamino-2,6-dideoxy-<ster eo>beta</stereo>-<stereo>L</stereo>-idopyranosyl)-<stereo>beta</stereo>-<stereo>D</stereo>-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1<stereo>R</stereo>,2<stereo>R</stereo>,3<stereo> S</stereo>,4<stereo>R</stereo>,6<stereo>S</stereo> diastereoisomer). It is obtained from various <ital>Streptomyces</ital> species. A broad-spectrum antibiotic, it is used (generally as the sulfate sa lt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmanias is. ChEBI CHEBI:7934
      An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycycloh exane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate sa; lt) for the treatment of acute and c hronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:7934
      An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycycloh exane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chr onic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. ChEBI CHEBI:7934

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.6±0.1 g/cm3
Boiling Point: 939.8±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±0.6 mmHg at 25°C
Enthalpy of Vaporization: 155.1±6.0 kJ/mol
Flash Point: 522.2±34.3 °C
Index of Refraction: 1.676
Molar Refractivity: 140.8±0.4 cm3
#H bond acceptors: 19
#H bond donors: 18
#Freely Rotating Bonds: 9
#Rule of 5 Violations: 3
ACD/LogP: -3.27
ACD/LogD (pH 5.5): -11.48
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -9.85
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 347 Å2
Polarizability: 55.8±0.5 10-24cm3
Surface Tension: 106.4±5.0 dyne/cm
Molar Volume: 374.1±5.0 cm3

Click to predict properties on the Chemicalize site


Advertisement