ChemSpider 2D Image | MFCD06409252 | C29H34F3N3O5S

MFCD06409252

  • Molecular FormulaC29H34F3N3O5S
  • Average mass593.658 Da
  • Monoisotopic mass593.217102 Da
  • ChemSpider ID17237984

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1217457-86-7 [RN]
Acide trifluoroacétique - N-[4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-(1-naphtyl)benzoyl]-L-leucinate de méthyle (1:1) [French] [ACD/IUPAC Name]
GGTI 298 (trifluoroacetate salt)
L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester, compd. with 2,2,2-trifluoroacetic acid (1:1) [ACD/Index Name]
METHYL (2S)-2-[(4-{[(2R)-2-AMINO-3-SULFANYLPROPYL]AMINO}-2-(NAPHTHALEN-1-YL)PHENYL)FORMAMIDO]-4-METHYLPENTANOATE; TRIFLUOROACETIC ACID
Methyl N-[4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-(1-naphthyl)benzoyl]-L-leucinate trifluoroacetate (1:1) [ACD/IUPAC Name]
MFCD06409252
N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate
Trifluoressigsäure -methyl-N-[4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-(1-naphthyl)benzoyl]-L-leucinat (1:1) [German] [ACD/IUPAC Name]
[1217457-86-7] [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
G5169_SIGMA [DBID]
RX 781094 | [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 ?M respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells. Tocris Bioscience 2430
      CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 ?M respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells. Tocris Bioscience 2430
      CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 muM respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells. Tocris Bioscience 2430
      Enzymes Tocris Bioscience 2430
      Geranylgeranyltransferase I (GGTase I) inhibitor Tocris Bioscience 2430
      Protein Prenyltransferases Tocris Bioscience 2430
      Transferases Tocris Bioscience 2430

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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