ChemSpider 2D Image | alpha-Melanotropin | C77H109N21O19S

α-Melanotropin

  • Molecular FormulaC77H109N21O19S
  • Average mass1664.884 Da
  • Monoisotopic mass1663.792969 Da
  • ChemSpider ID17288804
  • defined stereocentres - 12 of 12 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

α-Melanotropin
4214
581-05-5 [RN]
L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl- [ACD/Index Name]
N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamid [German] [ACD/IUPAC Name]
N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide [ACD/IUPAC Name]
N-Acétyl-L-séryl-L-tyrosyl-L-séryl-L-méthionyl-L-α-glutamyl-L-histidyl-L-phénylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide [French] [ACD/IUPAC Name]
OVF025LA77
α-Melanocyte Stimulating Hormone
α-MSH
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  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      7-TM Receptors Tocris Bioscience 2584
      Endogenous melanocortin receptor agonist Tocris Bioscience 2584
      Endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, i ncluding TNF-?, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration. Tocris Bioscience 2584
      Endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-?, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration. Tocris Bioscience 2584
      Endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-alpha, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration. Tocris Bioscience 2584
      Melanocortin Receptors Tocris Bioscience 2584
      Peptide Receptors Tocris Bioscience 2584

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.5±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.682
Molar Refractivity: 425.9±0.5 cm3
#H bond acceptors: 40
#H bond donors: 26
#Freely Rotating Bonds: 51
#Rule of 5 Violations: 3
ACD/LogP: -1.77
ACD/LogD (pH 5.5): -7.56
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -6.78
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 668 Å2
Polarizability: 168.8±0.5 10-24cm3
Surface Tension: 66.0±7.0 dyne/cm
Molar Volume: 1124.5±7.0 cm3

Click to predict properties on the Chemicalize site





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