ChemSpider 2D Image | GSA 10 | C26H30N2O5

GSA 10

  • Molecular FormulaC26H30N2O5
  • Average mass450.527 Da
  • Monoisotopic mass450.215485 Da
  • ChemSpider ID17748409

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

300833-95-8 [RN]
4-[[(1-Hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]-benzoic acid propyl ester
4-{[(1-Hexyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinoléinyl)carbonyl]amino}benzoate de propyle [French] [ACD/IUPAC Name]
Benzoic acid, 4-[[(1-hexyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl)carbonyl]amino]-, propyl ester [ACD/Index Name]
GSA 10
GSA-10
MFCD01128015
Propyl 4-{[(1-hexyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl)carbonyl]amino}benzoate [ACD/IUPAC Name]
propyl 4-{[(1-hexyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)carbonyl]amino}benzoate
Propyl-4-{[(1-hexyl-4-hydroxy-2-oxo-1,2-dihydro-3-chinolinyl)carbonyl]amino}benzoat [German] [ACD/IUPAC Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BAS 00693245 [DBID]
CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 4918
      Smo receptor agonist Tocris Bioscience 4918
      Smoothened (Smo) receptor agonist (EC50 = 1.2 ?M). Does not recognize the classic cyclopamine (Cat. No. 1623) binding site. Does not promote Smo translocation to the primary cilium; is strongly potent iated by forskolin and cholera toxin. Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Tocris Bioscience 4918
      Smoothened (Smo) receptor agonist (EC50 = 1.2 ?M). Does not recognize the classic cyclopamine (Cat. No. 1623) binding site. Does not promote Smo translocation to the primary cilium; is strongly potentiated by forskolin and cholera toxin. Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Tocris Bioscience 4918
      Smoothened (Smo) receptor agonist (EC50 = 1.2 muM). Does not recognize the classic cyclopamine (Cat. No. 1623) binding site. Does not promote Smo translocation to the primary cilium; is strongly potentiated by forskolin and cholera toxin. Promotes differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Tocris Bioscience 4918
      Smoothened Receptors Tocris Bioscience 4918

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 620.2±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.9 mmHg at 25°C
Enthalpy of Vaporization: 96.6±3.0 kJ/mol
Flash Point: 328.9±31.5 °C
Index of Refraction: 1.610
Molar Refractivity: 126.0±0.3 cm3
#H bond acceptors: 7
#H bond donors: 2
#Freely Rotating Bonds: 11
#Rule of 5 Violations: 1
ACD/LogP: 5.79
ACD/LogD (pH 5.5): 4.19
ACD/BCF (pH 5.5): 586.04
ACD/KOC (pH 5.5): 2003.88
ACD/LogD (pH 7.4): 2.42
ACD/BCF (pH 7.4): 9.92
ACD/KOC (pH 7.4): 33.93
Polar Surface Area: 96 Å2
Polarizability: 49.9±0.5 10-24cm3
Surface Tension: 55.9±3.0 dyne/cm
Molar Volume: 363.2±3.0 cm3

Click to predict properties on the Chemicalize site


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