ChemSpider 2D Image | Dronedarone | C31H44N2O5S

Dronedarone

  • Molecular FormulaC31H44N2O5S
  • Average mass556.756 Da
  • Monoisotopic mass556.297119 Da
  • ChemSpider ID180996

More details:



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141626-36-0 [RN]
7382
dronedarona [Spanish] [INN]
Dronedarone [INN] [Wiki]
dronédarone [French] [INN]
dronedaronum [Latin] [INN]
JQZ1L091Y2
Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]- [ACD/Index Name]
N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-1-benzofuran-5-yl)methanesulfonamide
N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide [ACD/IUPAC Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D02537 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      C01BD07 Wikidata Q408637
    • Chemical Class:

      A member of the class of 1-benzofurans used for the treatment of cardiac arrhythmias. ChEBI CHEBI:50659
    • Bio Activity:

      Dronedarone(Multaq) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF. MedChem Express
      Dronedarone(Multaq) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF.; IC50 value:; Target: multichannel blocker MedChem Express HY-A0016
      Dronedarone(Multaq) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF.;IC50 value:;Target: multichannel blocker MedChem Express HY-A0016
      Others MedChem Express HY-A0016

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.1±0.1 g/cm3
Boiling Point: 683.9±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.1 mmHg at 25°C
Enthalpy of Vaporization: 100.3±3.0 kJ/mol
Flash Point: 367.4±34.3 °C
Index of Refraction: 1.564
Molar Refractivity: 158.4±0.4 cm3
#H bond acceptors: 7
#H bond donors: 1
#Freely Rotating Bonds: 18
#Rule of 5 Violations: 2
ACD/LogP: 7.58
ACD/LogD (pH 5.5): 3.13
ACD/BCF (pH 5.5): 26.40
ACD/KOC (pH 5.5): 49.99
ACD/LogD (pH 7.4): 3.98
ACD/BCF (pH 7.4): 185.38
ACD/KOC (pH 7.4): 350.97
Polar Surface Area: 97 Å2
Polarizability: 62.8±0.5 10-24cm3
Surface Tension: 45.2±3.0 dyne/cm
Molar Volume: 487.1±3.0 cm3

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