ChemSpider 2D Image | Proparacaine hydrochloride | C16H27ClN2O3

Proparacaine hydrochloride

  • Molecular FormulaC16H27ClN2O3
  • Average mass330.850 Da
  • Monoisotopic mass330.171021 Da
  • ChemSpider ID20811

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-(diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride
2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride (1:1) [ACD/IUPAC Name]
2-(Diethylamino)ethyl-3-amino-4-propoxybenzoathydrochlorid (1:1) [German] [ACD/IUPAC Name]
2-(Diethylamino)ethyl-3-amino-4-propoxybenzolcarboxylathydrochlorid
227-541-7 [EINECS]
3-amino-4-propoxybenzoate de 2-(diéthylamino)éthyle chlorhydrate
3-Amino-4-propoxybenzoate de 2-(diéthylamino)éthyle, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
5875-06-9 [RN]
ak-taine
Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1) [ACD/Index Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D02098 [DBID]
P4554_SIGMA [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Sodium Channel inhibitor TargetMol T0222

    • Bio Activity:

      Membrane Tranporter/Ion Channel MedChem Express HY-66012
      Membrane Tranporter/Ion Channel; MedChem Express HY-66012
      Membrane Transporter/Ion Channel TargetMol T0222
      Proparacaine Hydrochloride is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM. MedChem Express
      Proparacaine Hydrochloride is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.; IC50 Value: 3.4 mM(ED50) [1]; Target: Sodium Channel; in vitro: Proparacaine is more potent and less toxic than cocaine [1]. MedChem Express HY-66012
      Proparacaine Hydrochloride is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.;IC50 Value: 3.4 mM(ED50) [1];Target: Sodium Channel;In vitro: Proparacaine is more potent and less toxic than cocaine [1]. Proparacaine significantly increases in FHV-1 (P < 0.01), C. felis, and 28S rDNA Ct values when fusidic acid is used [2].;In vivo: Proparacaine inhibits corneal epithelial migration and adhesion through alteration of the actin cytoskeleton [3]. Proparacaine acts like bupivacaine or lidocaine and produces dose-related spinal blockades of motor function, proprioception and nociception. Intrathecal proxymetacaine also produces longer sensory blockade than motor blockade [4]. MedChem Express HY-66012
      Sodium Channel MedChem Express HY-66012
      Sodium Channel TargetMol T0222

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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