ChemSpider 2D Image | cyclobenzaprine | C20H22ClN

cyclobenzaprine

  • Molecular FormulaC20H22ClN
  • Average mass311.848 Da
  • Monoisotopic mass311.144073 Da
  • ChemSpider ID21168

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

0VE05JYS2P
10,11d-Amitriptyline Hydrochloride
1-propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1) [ACD/Index Name]
200-659-6 [EINECS]
228-264-4 [EINECS]
3-(5H-Dibenzo[a,d][7]annulen-5-yliden)-N,N-dimethyl-1-propanaminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
3-(5H-Dibenzo[a,d][7]annulen-5-yliden)-N,N-dimethylpropan-1-aminhydrochlorid
3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride (1:1) [ACD/IUPAC Name]
3-(5H-Dibenzo[a,d][7]annulén-5-ylidène)-N,N-diméthyl-1-propanamine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

6247987 [DBID]
C4542_SIGMA [DBID]
D00772 [DBID]
EU-0100303 [DBID]
NSC 169900 [DBID]
NSC 173379 [DBID]
NSC 78206 [DBID]
Prestwick_790 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      5-HT Receptor antagonist TargetMol T1509

    • Chemical Class:

      The hydrochloride salt of cyclobenzaprine. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:3997, CHEBI:3997

    • Bio Activity:

      5-HT Receptor MedChem Express HY-B0740
      5-HT Receptor TargetMol T1509
      Cyclobenzaprine Hcl is a skeletal muscle relaxant and a central nervous system (CNS) depressant. MedChem Express
      Cyclobenzaprine Hcl is a skeletal muscle relaxant and a central nervous system (CNS) depressant.; Target: 5-HT Receptor 2A; Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. MedChem Express HY-B0740
      Cyclobenzaprine Hcl is a skeletal muscle relaxant and a central nervous system (CNS) depressant.;Target: 5-HT Receptor 2ACyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine was thought to be an alpha 2-adrenoceptor agonist that reduced muscle tone by decreasing the activity of descending noradrenergic neurons. Cyclobenzaprine reduced the monosynaptic reflex amplitude dose dependently and this effect was not inhibited by the alpha 2-adrenoceptor antagonists idazoxan and yohimbine. Cyclobenzaprine-induced monosynaptic reflex depression was not attenuated by noradrenergic neuronal lesions produced by 6-hydroxydopamine. Cyclobenzaprine is a 5-HT2 receptor antagonist and that its muscle relaxant effect is due to inhibition of serotonergic, not noradrenergic, descending systems in the spinal cord [1]. The inhibitory effects of cyclobenzaprine on mono- and polysynaptic reflex potentials are due to the inhibition of descending seroto MedChem Express HY-B0740
      GPCR/G protein MedChem Express HY-B0740
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0740
      Neuroscience TargetMol T1509

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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