ChemSpider 2D Image | CID 25010775 | C18H28ClN3O3

CID 25010775

  • Molecular FormulaC18H28ClN3O3
  • Average mass369.886 Da
  • Monoisotopic mass369.181915 Da
  • ChemSpider ID21447433

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1135242-13-5 [RN]
1-Piperidinecarboxylic acid, 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-, ethyl ester, hydrochloride (1:1) [ACD/Index Name]
4-({2-[(2-Méthylbenzoyl)amino]éthyl}amino)-1-pipéridinecarboxylate d'éthyle, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester monohydrochloride
CID 25010775
Ethyl 4-({2-[(2-methylbenzoyl)amino]ethyl}amino)-1-piperidinecarboxylate hydrochloride (1:1) [ACD/IUPAC Name]
ETHYL 4-({2-[(2-METHYLPHENYL)FORMAMIDO]ETHYL}AMINO)PIPERIDINE-1-CARBOXYLATE HYDROCHLORIDE
Ethyl-4-({2-[(2-methylbenzoyl)amino]ethyl}amino)-1-piperidincarboxylathydrochlorid (1:1) [German] [ACD/IUPAC Name]
MFCD17215959
ML071 hydrochloride
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

PubChem Substance ID 329825761 [DBID]
  • References
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 4295
      Acetylcholine (Muscarinic) Receptors Tocris Bioscience 4295
      Acetylcholine Muscarinic Receptors Tocris Bioscience 4295
      Biochemicals & small molecules/Agonists & activators Hello Bio HB1498
      GPCR/G protein MedChem Express HY-19752A
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-19752A
      M1 Receptors Tocris Bioscience 4295
      mAChR MedChem Express HY-19752A
      Positive allosteric modulator of M1 receptors Tocris Bioscience 4295
      Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 ?M. Potentiates NMDA receptor currents in hippocampal neurons; activi ty reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant. Tocris Bioscience 4295
      Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 ?M. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant. Tocris Bioscience 4295
      Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 muM. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant. Tocris Bioscience 4295
      Potent and selective M<sub>1</sub> muscarinic receptor allosteric agonist (EC<sub>50</sub> = 198 nM). Binds to the orthosteric ACh site at high concentrations to act as an antagonist. Reverses contextual fear conditioning deficits. Shows cognitive enhancing actions. Blood-brain barrier permeable. Hello Bio HB1498
      Potent, selective M<sub>1</sub> receptor allosteric agonist Hello Bio HB1498
      Receptors & Transporters/G protein coupled receptors/ACh muscarinic Hello Bio HB1498
      VU0357017 hydrochloride is a highly selective M1 agonists that appear to act at an allosteric site to activate the receptor (EC50 = 477 ? 172 nM; pEC50 = 6.37 ? 0.15).; IC50 value: 477 ? 172 nM (EC50) [1]; Target: M1; in vitro: VU0357017 is a M1-selective agonists that appear to activate M1 through actions at an allosteric site. MedChem Express HY-19752A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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