ChemSpider 2D Image | N-Hydroxy-9-pentofuranosyl-9H-purin-6-amine | C10H13N5O5

N-Hydroxy-9-pentofuranosyl-9H-purin-6-amine

  • Molecular FormulaC10H13N5O5
  • Average mass283.241 Da
  • Monoisotopic mass283.091675 Da
  • ChemSpider ID244573

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

9H-Purin-6-amine, N-hydroxy-9-pentofuranosyl- [ACD/Index Name]
N-Hydroxy-9-pentofuranosyl-9H-purin-6-amin [German] [ACD/IUPAC Name]
N-Hydroxy-9-pentofuranosyl-9H-purin-6-amine [ACD/IUPAC Name]
N-Hydroxy-9-pentofuranosyl-9H-purin-6-amine [French] [ACD/IUPAC Name]
(C-6-(hydroxyamino)-purine ribofuranoside)2-(6-Hydroxyamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2-(6-Hydroxyamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2-(6-Hydroxyamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (HAPR)
2-[6-(hydroxyamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
2-[6-(hydroxyamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydro-3,4-furandiol
24822-51-3 [RN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

NSC 529410 [DBID]
NSC126876 [DBID]
NSC529410 [DBID]
ZINC00040153 [DBID]

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 2.1±0.1 g/cm3
Boiling Point: 703.7±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.3 mmHg at 25°C
Enthalpy of Vaporization: 108.1±3.0 kJ/mol
Flash Point: 379.4±35.7 °C
Index of Refraction: 1.898
Molar Refractivity: 62.0±0.5 cm3
#H bond acceptors: 10
#H bond donors: 5
#Freely Rotating Bonds: 3
#Rule of 5 Violations: 2
ACD/LogP: -1.30
ACD/LogD (pH 5.5): -1.06
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 5.99
ACD/LogD (pH 7.4): -1.91
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 146 Å2
Polarizability: 24.6±0.5 10-24cm3
Surface Tension: 109.1±7.0 dyne/cm
Molar Volume: 133.4±7.0 cm3

Predicted data is generated using the US Environmental Protection Agency’s EPISuite™

                        
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  -1.42

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  568.43  (Adapted Stein & Brown method)
    Melting Pt (deg C):  244.57  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  4.24E-016  (Modified Grain method)
    Subcooled liquid VP: 1.02E-013 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  1.232e+004
       log Kow used: -1.42 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  1e+006 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Imidazoles

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   2.23E-025  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  1.283E-020 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  -1.42  (KowWin est)
  Log Kaw used:  -23.040  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  21.620
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   0.7415
   Biowin2 (Non-Linear Model)     :   0.2517
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   3.0445  (weeks       )
   Biowin4 (Primary Survey Model) :   3.8177  (days        )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.4700
   Biowin6 (MITI Non-Linear Model):   0.0695
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.9701
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  1.36E-011 Pa (1.02E-013 mm Hg)
  Log Koa (Koawin est  ): 21.620
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  2.21E+005 
       Octanol/air (Koa) model:  1.02E+009 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  1 
       Mackay model           :  1 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 238.3639 E-12 cm3/molecule-sec
      Half-Life =     0.045 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.538 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Fraction sorbed to airborne particulates (phi): 1 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  10
      Log Koc:  1.000 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 0.500 (BCF = 3.162)
       log Kow used: -1.42 (estimated)

 Volatilization from Water:
    Henry LC:  2.23E-025 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 4.419E+021  hours   (1.841E+020 days)
    Half-Life from Model Lake :  4.82E+022  hours   (2.008E+021 days)

 Removal In Wastewater Treatment:
    Total removal:               1.85  percent
    Total biodegradation:        0.09  percent
    Total sludge adsorption:     1.75  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       7.51e-011       1.08         1000       
   Water     39              360          1000       
   Soil      60.9            720          1000       
   Sediment  0.0713          3.24e+003    0          
     Persistence Time: 579 hr




                    

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