There will be scheduled maintenance work beginning on Wednesday 26th February 2020 from 11:00 AM through to 12.00 PM (GMT).

During this time, you may not be able to log into ChemSpider. We apologise for any inconvenience this might cause and thank you for your patience.

ChemSpider 2D Image | Quizartinib | C29H32N6O4S


  • Molecular FormulaC29H32N6O4S
  • Average mass560.667 Da
  • Monoisotopic mass560.220581 Da
  • ChemSpider ID24640357

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-[5-(2-Methyl-2-propanyl)-1,2-oxazol-3-yl]-3-(4-{7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)harnstoff [German] [ACD/IUPAC Name]
1-[5-(2-Methyl-2-propanyl)-1,2-oxazol-3-yl]-3-(4-{7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea [ACD/IUPAC Name]
1-[5-(2-Méthyl-2-propanyl)-1,2-oxazol-3-yl]-3-(4-{7-[2-(4-morpholinyl)éthoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phényl)urée [French] [ACD/IUPAC Name]
950769-58-1 [RN]
Quizartinib [USAN] [Wiki]
Urea, N-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]- [ACD/Index Name]

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AC010220 [DBID]
AC220 [DBID]
AC 220 [DBID]
AC-220 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Target Organs:

      FLT3 inhibitor TargetMol T2066
    • Chemical Class:

      A member of the class of phenylureas that is urea in which one of the amino groups has been substituted by a 5-<ital>tert</ital>-butyl-1,2-oxazol-3-yl group while the other has been substituted by a p henyl group substituted at the <ital>para</ital>- position by an imidazo[2,1-<ital>b</ital>][1,3]benzothiazol-2-yl group that, in turn, is substituted at position 7 by a 2-(morpholin-4-yl)ethoxy group . ChEBI CHEBI:90217
    • Bio Activity:

      FLT3 MedChem Express HY-13001
      FLT3 TargetMol T2066
      Protein Tyrosine Kinase/RTK MedChem Express HY-13001
      Protein Tyrosine Kinase/RTK; MedChem Express HY-13001
      Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFR?, PDGFR?, RET, and CSF-1R. MedChem Express HY-13001
      Tyrosine Kinase/Adaptors TargetMol T2066

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.691
Molar Refractivity: 153.8±0.5 cm3
#H bond acceptors: 10
#H bond donors: 2
#Freely Rotating Bonds: 8
#Rule of 5 Violations: 2
ACD/LogP: 4.03
ACD/LogD (pH 5.5): 2.82
ACD/BCF (pH 5.5): 31.43
ACD/KOC (pH 5.5): 131.24
ACD/LogD (pH 7.4): 4.49
ACD/BCF (pH 7.4): 1455.10
ACD/KOC (pH 7.4): 6076.08
Polar Surface Area: 134 Å2
Polarizability: 61.0±0.5 10-24cm3
Surface Tension: 55.6±7.0 dyne/cm
Molar Volume: 402.0±7.0 cm3

Click to predict properties on the Chemicalize site