ChemSpider 2D Image | DA0292500 | C13H18ClN

DA0292500

  • Molecular FormulaC13H18ClN
  • Average mass223.742 Da
  • Monoisotopic mass223.112778 Da
  • ChemSpider ID24931

  • defined stereocentres - 1 of 1 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(-)-(R)-N,α-Dimethyl-N-2-propynylphenethylamine hydrochloride
(-)-(R)-N,α-Dimethyl-N-2-propynylphenethylamine monohydrochloride
(-)-Deprenil hydrochloride
(-)-Deprenyl hydrochloride
(-)-selegiline hydrochloride
(R)-(-)-Deprenyl hydrochloride
(R)-(-)-N,α-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride
(R)-(−)-N,α-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride
(R)-selegiline hydrochloride
14611-52-0 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D00785 [DBID]
DRG-0237 [DBID]
E-250 [DBID]
FPF-1100 [DBID]
HSDB 7183 [DBID]
M003_SIGMA [DBID]
Prestwick_846 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Appearance:

      white or almost white solid LGC Standards LGCFOR0216.00

    • Bio Activity:

      Enzymes Tocris Bioscience 1095
      MAO-B inhibitor Tocris Bioscience 1095
      Monoamine Oxidase Tocris Bioscience 1095
      Monoamine Oxidase MedChem Express HY-14199
      Neuronal Signaling; MedChem Express HY-14199
      Oxygenases/Oxidases Tocris Bioscience 1095
      R-(-)-Deprenyl Hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B). MedChem Express
      R-(-)-Deprenyl Hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B).;Target: Monoamine oxidase B(-)-Deprenyl (selegiline) is an irreversible inhibitor of monoamine oxidase (MAO) B. (-)-Deprenyl in much lower concentrations needed to induce MAO-B inhibition (10(-9) to 10(-13) M) potently inhibits MPTP or serum withdrawal induced apoptosis in tissue cultures of neuro-ectodermal origin (PC12, M1, M2058) [1]. when locomotor activity induced by levodopa was examined on a rodent model of Parkinson's disease, pretreatment of the animals with nonselective doses of deprenyl caused an enhancement of the antiparkinsonian action of levodopa [2]. (-)Deprenyl is a highly potent and selective, irreversible inhibitor of B-type monoamine oxidase (MAO), a predominantly glial enzyme in the brain. The activity of this enzyme significantly increases with age. (-)Deprenyl, the first selective inhibitor of MAO-B described in the literature, has become a universally used research tool for MedChem Express HY-14199
      Selective inhibitor of monoamine oxidase B (MAO-B). Tocris Bioscience 1095

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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