ChemSpider 2D Image | Apabetalone | C20H22N2O5

Apabetalone

  • Molecular FormulaC20H22N2O5
  • Average mass370.399 Da
  • Monoisotopic mass370.152863 Da
  • ChemSpider ID25069708

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1044870-39-4 [RN]
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-3,4-dihydroquinazolin-4-one
2-[4-(2-Hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-3H-quinazolin-4-one
2-[4-(2-Hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(1H)-chinazolinon [German] [ACD/IUPAC Name]
2-[4-(2-Hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(1H)-quinazolinone [ACD/IUPAC Name]
2-[4-(2-Hydroxyéthoxy)-3,5-diméthylphényl]-5,7-diméthoxy-4(1H)-quinazolinone [French] [ACD/IUPAC Name]
4(3H)-Quinazolinone, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy- [ACD/Index Name]
8R4A7GDZ1D
apabetalona [Spanish] [INN]
Apabetalone [INN] [USAN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

9884 [DBID]
CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Epigenetic Reader Domain inhibitor TargetMol T2480

    • Bio Activity:

      BET bromodomain MedChem Express HY-16652
      BRD2 TargetMol T2480
      Cell Cycle/DNA Damage MedChem Express HY-16652
      Cell Cycle/DNA Damage; MedChem Express HY-16652
      Chromatin/Epigenetic TargetMol T2480
      RVX-208(RVX 000222) is a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo; is a BET bromodomain antagonist. MedChem Express
      RVX-208(RVX 000222) is a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo; is a BET bromodomain antagonist.; IC50 value:; Target: BET bromodomain antagonist; The RVX-208 induced apoA-I messenger ribonucleic acid and protein synthesis in HepG2 cells, leading to increased levels of pre-beta-migrating and alpha-lipoprotein particles containing apoA-I (LpA-I) in spent media. MedChem Express HY-16652

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.596
Molar Refractivity: 98.3±0.5 cm3
#H bond acceptors: 7
#H bond donors: 2
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 0
ACD/LogP: 2.04
ACD/LogD (pH 5.5): 2.31
ACD/BCF (pH 5.5): 33.78
ACD/KOC (pH 5.5): 432.31
ACD/LogD (pH 7.4): 2.31
ACD/BCF (pH 7.4): 33.60
ACD/KOC (pH 7.4): 430.01
Polar Surface Area: 89 Å2
Polarizability: 39.0±0.5 10-24cm3
Surface Tension: 43.2±7.0 dyne/cm
Molar Volume: 288.9±7.0 cm3

Click to predict properties on the Chemicalize site


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