ChemSpider 2D Image | Pancuronium bromide | C35H60Br2N2O4

Pancuronium bromide

  • Molecular FormulaC35H60Br2N2O4
  • Average mass732.670 Da
  • Monoisotopic mass730.291992 Da
  • ChemSpider ID25453

  • Charge - Charge

    defined stereocentres - 10 of 10 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(1-methylpiperidinium-1-yl)androstane dibromide
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-2,16-bis(1-methyl-1-piperidiniumyl)androstandibromid [German] [ACD/IUPAC Name]
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-2,16-bis(1-methyl-1-piperidiniumyl)androstane dibromide [ACD/IUPAC Name]
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-2,16-bis(1-methylpiperidinium-1-yl)androstane dibromide
1,1'-(3a,17b-Dihydroxy-5a-androstan-2b,16b-ylene)bis[1-methylpiperidinium] Dibromide Diacetate
1,1'-[(2b,3a,5a,16b,17b)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis[1-methylpiperidinium] Dibromide
1,1'-[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-Bis(acetyloxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-2,16-diyl]bis(1-methylpiperidinium)dibromid
1,1'-[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-bis(acetyloxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-2,16-diyl]bis(1-methylpiperidinium) dibromide
1,1'-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)androstane-2,16-diyl]bis(1-methylpiperidinium) dibromide
15500-66-0 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2489 [DBID]
4226892 [DBID]
D00492 [DBID]
EU-0100887 [DBID]
HSDB 3244 [DBID]
NA 97 [DBID]
NSC 293162 [DBID]
P1918_SIGMA [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      A bromide salt consisting of two bromide ions and one pancuronium dication. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:7908, CHEBI:7908
      Cholinergic EU-OpenScreen [P 1918]

    • Bio Activity:

      Membrane Tranporter/Ion Channel MedChem Express HY-B0429
      Membrane Tranporter/Ion Channel; Neuronal Signaling; MedChem Express HY-B0429
      nAChR MedChem Express HY-B0429
      Pancuronium Dibromide is a bis-quaternary steroid that is a competitive nicotinic antagonist. MedChem Express
      Pancuronium Dibromide is a bis-quaternary steroid that is a competitive nicotinic antagonist.; Target: nAChR; Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skele tal muscle relaxant. MedChem Express HY-B0429
      Pancuronium Dibromide is a bis-quaternary steroid that is a competitive nicotinic antagonist.;Target: nAChRPancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant. Pancuronium dibromide interrupts neuromuscular transmission by competing with acetylcholine for receptor sites on the motor end-plate. Pancuronium dibromide is a non-depolarizing agent. Pancuronium is a typical non-depolarizing curare-mimetic muscle relaxant. It acts as a competitive acetylcholine antagonist on neuromuscular junctions, displacing acetylcholine (hence competitive) from its post-synaptic nicotinic acetylcholine receptors. It is (unlike suxamethonium) a non-depolarizing agent, which means that it causes no spontaneous depolarizations upon association with the nicotinic receptor in neuromuscular junction, thus producing no muscle fasciculations upon administration [1-3]. MedChem Express HY-B0429

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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