ChemSpider 2D Image | 2-(1-oxoeicosa-5,8,11,14-tetraenylamino)acetic acid | C22H35NO3

2-(1-oxoeicosa-5,8,11,14-tetraenylamino)acetic acid

  • Molecular FormulaC22H35NO3
  • Average mass361.518 Da
  • Monoisotopic mass361.261688 Da
  • ChemSpider ID27472362

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-(1-oxoeicosa-5,8,11,14-tetraenylamino)acetic acid
Glycine, N-[(5E,8E,11E,14E)-1-oxo-5,8,11,14-eicosatetraen-1-yl]- [ACD/Index Name]
N-[(5E,8E,11E,14E)-5,8,11,14-Icosatetraenoyl]glycin [German] [ACD/IUPAC Name]
N-[(5E,8E,11E,14E)-5,8,11,14-Icosatetraenoyl]glycine [ACD/IUPAC Name]
N-[(5E,8E,11E,14E)-5,8,11,14-Icosatetraenoyl]glycine [French] [ACD/IUPAC Name]
1159908-44-7 [RN]
179113-91-8 [RN]
2-(icosa-5,8,11,14-tetraenamido)acetic acid
2-[[(5E,8E,11E,14E)-Icosa-5,8,11,14-tetraenoyl]amino]acetic acid
Arachidonoyl Glycine-d8
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

  • References
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB0439
      Endogenous GLYT2 inhibitor (IC<sub>50</sub> = 3 &micro;M) that displays little activity at GLYT1. Also reversibly inhibits Ca<sub>v</sub>3.1, Ca<sub>v</sub>3.2 and Ca<sub>v</sub>3.3 currents (EC<sub>50</sub> values are 1.3 &micro;M, 600 nM and 1.6 &micro;M respectively). Novel insulin secretagogue and natural ligand for orphan G-protein-coupled receptor, GPR18. Displays analgesic properties. Hello Bio HB0439
      Endogenous GLYT2 inhibitor / Ca<sub>v</sub>3.1 / 3.2 / 3.3 current inhibitor Hello Bio HB0439
      Receptors & Transporters/Transporters/Glycine Hello Bio HB0439

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.0±0.1 g/cm3
Boiling Point: 560.9±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±3.3 mmHg at 25°C
Enthalpy of Vaporization: 92.2±6.0 kJ/mol
Flash Point: 293.0±30.1 °C
Index of Refraction: 1.508
Molar Refractivity: 109.4±0.3 cm3
#H bond acceptors: 4
#H bond donors: 2
#Freely Rotating Bonds: 16
#Rule of 5 Violations: 1
ACD/LogP: 5.88
ACD/LogD (pH 5.5): 3.16
ACD/BCF (pH 5.5): 43.55
ACD/KOC (pH 5.5): 120.64
ACD/LogD (pH 7.4): 1.79
ACD/BCF (pH 7.4): 1.85
ACD/KOC (pH 7.4): 5.11
Polar Surface Area: 66 Å2
Polarizability: 43.4±0.5 10-24cm3
Surface Tension: 38.1±3.0 dyne/cm
Molar Volume: 366.7±3.0 cm3

Click to predict properties on the Chemicalize site


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