ChemSpider 2D Image | Fostemsavir tromethamine | C29H37N8O11P

Fostemsavir tromethamine

  • Molecular FormulaC29H37N8O11P
  • Average mass704.625 Da
  • Monoisotopic mass704.231934 Da
  • ChemSpider ID28637754

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

({3-[2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}methoxy)phosphonic acid; 2-amino-2-(hydroxymethyl)propane-1,3-diol
{3-[(4-Benzoyl-1-piperazinyl)(oxo)acetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}methyl dihydrogen phosphate - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) [ACD/IUPAC Name]
{3-[(4-Benzoyl-1-piperazinyl)(oxo)acetyl]-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}methyldihydrogenphosphat --2-amino-2-(hydroxymethyl)-1,3-propandiol (1:1) [German] [ACD/IUPAC Name]
1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propane diol (1:1) [ACD/Index Name]
2X513P36U0
864953-39-9 [RN]
BMS-663068-03
Dihydrogénophosphate de {3-[2-(4-benzoyl-1-pipérazinyl)-2-oxoacétyl]-4-méthoxy-7-(3-méthyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl}méthyle - 2-amino-2-(hydroxyméthyl)-1,3-propanediol (1:1 ) [French] [ACD/IUPAC Name]
Fostemsavir tromethamine [USAN]
Rukobia [Trade name]
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  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Anti-infection MedChem Express HY-15440B
      Anti-infection; MedChem Express HY-15440B
      BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. MedChem Express http://www.medchemexpress.com/gdc-0834-racemate.html, HY-15440B
      BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. ;IC50 Value:;Target: HIVBMS-663068 is a prodrug for BMS-626529 which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Administration of BMS-663068 for 8 days with or without ritonavir resulted in substantial declines in plasma HIV-1 RNA levels and was generally well tolerated. Longer-term clinical trials of BMS-663068 as part of combination antiretroviral therapy are warranted. MedChem Express HY-15440B
      HIV MedChem Express HY-15440B

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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