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ChemSpider 2D Image | Solcitinib | C22H23N5O2

Solcitinib

  • Molecular FormulaC22H23N5O2
  • Average mass389.450 Da
  • Monoisotopic mass389.185181 Da
  • ChemSpider ID31389944

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

10047
1206163-45-2 [RN]
3V7GQ1260K
Cyclopropanecarboxamide, N-[5-[4-[(3,3-dimethyl-1-azetidinyl)carbonyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]- [ACD/Index Name]
G154578
GLPG0778
GSK2586184A
N-(5-{4-[(3,3-Dimethyl-1-azetidinyl)carbonyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropancarboxamid [German] [ACD/IUPAC Name]
N-(5-{4-[(3,3-Dimethyl-1-azetidinyl)carbonyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide [ACD/IUPAC Name]
N-(5-{4-[(3,3-Diméthyl-1-azétidinyl)carbonyl]phényl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide [French] [ACD/IUPAC Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

PubChem Substance ID 329825761 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      5 Axon Medchem 2539
      H303;H313;H317;H333;H334;H335;H383 Axon Medchem 2539
      no pictogram Axon Medchem 2539
      P101;P102;P103;P260;P262;P263;P264;P270;P280;P304;P312;P350 Axon Medchem 2539
      Warning Axon Medchem 2539
    • Bio Activity:

      JAK MedChem Express HY-16755
      JAK/STAT Signaling MedChem Express HY-16755
      JAK/STAT Signaling; MedChem Express HY-16755
      Solcitinib is a selective Janus kinase 1 (JAK1) inhibitor, for the treatment of psoriasis, lupus, and ulcerative colitis.; Targer: JAK1 MedChem Express HY-16755
      Solcitinib is a selective Janus kinase 1 (JAK1) inhibitor, for the treatment of psoriasis, lupus, and ulcerative colitis.;Targer: JAK1 MedChem Express HY-16755

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.723
Molar Refractivity: 110.1±0.5 cm3
#H bond acceptors: 7
#H bond donors: 1
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 1.51
ACD/LogD (pH 5.5): 1.90
ACD/BCF (pH 5.5): 16.45
ACD/KOC (pH 5.5): 257.98
ACD/LogD (pH 7.4): 1.80
ACD/BCF (pH 7.4): 13.05
ACD/KOC (pH 7.4): 204.72
Polar Surface Area: 80 Å2
Polarizability: 43.7±0.5 10-24cm3
Surface Tension: 58.5±7.0 dyne/cm
Molar Volume: 277.9±7.0 cm3

Click to predict properties on the Chemicalize site






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