ChemSpider 2D Image | (1'R,2R,4E,4'S,5S,6S,8'R,10'Z,13'R,14'Z,16'Z,20'R,21'R,24'S)-21',24'-Dihydroxy-4-(methoxyimino)-5,11',13',22'-tetramethyl-6-[(2E)-4-methyl-2-penten-2-yl]-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,1 9]trioxatetracyclo[15.6.1.1~4,8~.0~20,24~]pentacosa[10,14,16,22]tetraen]-2'-one | C37H53NO8

(1'R,2R,4E,4'S,5S,6S,8'R,10'Z,13'R,14'Z,16'Z,20'R,21'R,24'S)-21',24'-Dihydroxy-4-(methoxyimino)-5,11',13',22'-tetramethyl-6-[(2E)-4-methyl-2-penten-2-yl]-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,1 9]trioxatetracyclo[15.6.1.14,8.020,24]pentacosa[10,14,16,22]tetraen]-2'-one

  • Molecular FormulaC37H53NO8
  • Average mass639.819 Da
  • Monoisotopic mass639.377136 Da
  • ChemSpider ID32700517

  • Double-bond stereo - Double-bond stereo

    defined stereocentres - 10 of 10 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(1'R,2R,4E,4'S,5S,6S,8'R,10'Z,13'R,14'Z,16'Z,20'R,21'R,24'S)-21',24'-Dihydroxy-4-(methoxyimino)-5,11',13',22'-tetramethyl-6-[(2E)-4-methyl-2-penten-2-yl]-3,4,5,6-tetrahydro-2'H-spiro[pyran-2,6'-[3,7,1 ;9]trioxatetracyclo[15.6.1.14,8.020,24]pentacosa[10,14,16,22]tetraen]-2'-one [ACD/IUPAC Name]
1057086-19-7 [RN]
CL301423
cydectin
Doramectin [INN] [Wiki]
MFCD00866560
Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
Moxidectin [Wiki]
ProHeart 6
ProHeart 6;CL301423;Cydectin
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Anti-infection MedChem Express HY-B0777
      Anti-infection; MedChem Express HY-B0777
      Antiparasitic MedChem Express HY-B0777
      Moxidectin(ProHeart 6; CL301423; Cydectin) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. MedChem Express
      Moxidectin(ProHeart 6; CL301423; Cydectin) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.; IC50 value:; Target: Anti-parasitic; Moxidectin is a semisynthetic derivative of nemadectin, which is produced by fermentation by Streptomyces cyano-griseus. MedChem Express HY-B0777
      Moxidectin(ProHeart 6; CL301423; Cydectin) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.;IC50 value:;Target: Anti-parasiticMoxidectin is a semisynthetic derivative of nemadectin, which is produced by fermentation by Streptomyces cyano-griseus. Moxidectin treats and controls some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite. Studies of moxidectin show the side effects vary by animal and may be affected by the product?s formulation, application method and dosage. MedChem Express HY-B0777

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 790.0±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±6.2 mmHg at 25°C
Enthalpy of Vaporization: 130.9±6.0 kJ/mol
Flash Point: 431.6±35.7 °C
Index of Refraction: 1.581
Molar Refractivity: 172.5±0.5 cm3
#H bond acceptors: 9
#H bond donors: 2
#Freely Rotating Bonds: 3
#Rule of 5 Violations: 2
ACD/LogP: 8.43
ACD/LogD (pH 5.5): 7.29
ACD/BCF (pH 5.5): 204661.25
ACD/KOC (pH 5.5): 220401.72
ACD/LogD (pH 7.4): 7.29
ACD/BCF (pH 7.4): 204658.78
ACD/KOC (pH 7.4): 220399.06
Polar Surface Area: 116 Å2
Polarizability: 68.4±0.5 10-24cm3
Surface Tension: 41.3±7.0 dyne/cm
Molar Volume: 517.2±7.0 cm3

Click to predict properties on the Chemicalize site


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