ChemSpider 2D Image | NSI-189 | C22H30N4O

NSI-189

  • Molecular FormulaC22H30N4O
  • Average mass366.500 Da
  • Monoisotopic mass366.241974 Da
  • ChemSpider ID32701740

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanon [German] [ACD/IUPAC Name]
(4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone [ACD/IUPAC Name]
(4-Benzyl-1-pipérazinyl){2-[(3-méthylbutyl)amino]-3-pyridinyl}méthanone [French] [ACD/IUPAC Name]
1270138-40-3 [RN]
Methanone, [2-[(3-methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]- [ACD/Index Name]
NSI-189 [Wiki]
UNII:YVE9U408ZL
YVE9U408ZL
(4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone
(4-benzylpiperazin-1-yl)(2-(isopentylamino)pyridin-3-yl)methanone (NSI-189)
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Appearance:

      Not Available Novochemy [NC-41407]
      White Powder Novochemy [NC-42751]
    • Safety:

      20/21/22 Novochemy [NC-41407] , [NC-42751]
      20/21/36/37/39 Novochemy [NC-41407] , [NC-42751]
      GHS07; GHS09 Novochemy [NC-41407] , [NC-42751]
      H304; H403 Novochemy [NC-41407]
      H332; H403 Novochemy [NC-42751]
      P102; P210; P262; P270; P302+P352; P308+P344 Novochemy [NC-42751]
      P332+P313; P305+P351+P338 Novochemy [NC-41407]
      R22 Novochemy [NC-41407]
      Warning Novochemy [NC-41407] , [NC-42751]
      Xn Novochemy [NC-42751]
    • Target Organs:

      Others TargetMol T1833
    • Bio Activity:

      NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine. MedChem Express
      NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.; IC50 value:; Target: ; in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. MedChem Express HY-13999
      NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.;IC50 value:;Target: ;In vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].;In vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3]. MedChem Express HY-13999
      Others MedChem Express HY-13999
      Others TargetMol T1833

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.1±0.1 g/cm3
Boiling Point: 534.7±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.4 mmHg at 25°C
Enthalpy of Vaporization: 81.1±3.0 kJ/mol
Flash Point: 277.2±30.1 °C
Index of Refraction: 1.601
Molar Refractivity: 110.6±0.3 cm3
#H bond acceptors: 5
#H bond donors: 1
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 0
ACD/LogP: 4.13
ACD/LogD (pH 5.5): 3.45
ACD/BCF (pH 5.5): 176.34
ACD/KOC (pH 5.5): 938.92
ACD/LogD (pH 7.4): 4.07
ACD/BCF (pH 7.4): 722.86
ACD/KOC (pH 7.4): 3848.90
Polar Surface Area: 48 Å2
Polarizability: 43.8±0.5 10-24cm3
Surface Tension: 51.8±3.0 dyne/cm
Molar Volume: 323.0±3.0 cm3

Click to predict properties on the Chemicalize site





Feedback Form