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Inherent Properties, Identifiers and References
ChemSpider ID: 333607
Empirical Formula: C19H16O4
Molecular Weight: 308.3279
Nominal Mass: 308 Da
Average Mass: 308.3279 Da
Monoisotopic Mass: 308.104859 Da
Quick Links: Permalink Similar Isomers
Systematic Name: 1-(2-hydroxy-4,6-dimethoxy-phenyl)naphthalene-2-carbaldehyde
SMILES: O=Cc3c(c1c(O)cc(OC)cc1OC)c2ccccc2cc3
InChI: InChI=1/C19H16O4/c1-22-14-9-16(21)19(17(10-14)23-2)18-13(11-20)8-​7-12-5-3-4-6-15(12)18/h3-11,21H,1-2H3
InChIKey: BFXXQLDFQRKMAJ-UHFFFAOYAW
(Details...) Original Reference(s)
(Details...) Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

"OMe-alde​hyde" (TH​ 3)

(Details...) Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

NSC656558

(Details...) Predicted Properties
LogP: ACD/LogP: 2.89
XLogP: 4.30
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): ACD/LogD (pH 7.4):
ACD/BCF (pH 5.5): ACD/BCF (pH 7.4):
ACD/KOC (pH 5.5): ACD/KOC (pH 7.4):
#H bond acceptors: 4 #H bond donors: 1
#Freely Rotating Bonds: 5 Polar Surface Area: 44.76 Å2
Index of Refraction: 1.655 Molar Refractivity: 90.67 cm3
Molar Volume: 246.9 cm3 Polarizability: 35.94 10-24cm3
Surface Tension: 50.3 dyne/cm Density: 1.248 g/cm3
Flash Point: 175.4 °C Enthalpy of Vaporization: 77.66 kJ/mol
Boiling Point: 483.1 °C at 760 mmHg Vapour Pressure: 5.89E-10 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  4.33

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  478.79  (Adapted Stein & Brown method)
    Melting Pt (deg C):  202.69  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  1.79E-010  (Modified Grain method)
    Subcooled liquid VP: 1.35E-008 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  8.336
       log Kow used: 4.33 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  6.268 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Aldehydes
       Phenols

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   3.67E-014  atm-m3/mole
   Group Method:   1.25E-011  atm-m3/mole
 Henrys LC [VP/WSol estimate using EPI values]:  8.712E-012 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  4.33  (KowWin est)
  Log Kaw used:  -11.824  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  16.154
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   1.2650
   Biowin2 (Non-Linear Model)     :   1.0000
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.4802  (weeks-months)
   Biowin4 (Primary Survey Model) :   3.7935  (days        )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.7275
   Biowin6 (MITI Non-Linear Model):   0.6229
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.4728
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  1.8E-006 Pa (1.35E-008 mm Hg)
  Log Koa (Koawin est  ): 16.154
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  1.67 
       Octanol/air (Koa) model:  3.5E+003 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.984 
       Mackay model           :  0.993 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 228.5117 E-12 cm3/molecule-sec
      Half-Life =     0.047 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.562 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 0.988 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  1.221E+004
      Log Koc:  4.087 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 2.635 (BCF = 432)
       log Kow used: 4.33 (estimated)

 Volatilization from Water:
    Henry LC:  1.25E-011 atm-m3/mole  (estimated by Group SAR Method)
    Half-Life from Model River: 8.225E+007  hours   (3.427E+006 days)
    Half-Life from Model Lake : 8.972E+008  hours   (3.738E+007 days)

 Removal In Wastewater Treatment:
    Total removal:              46.89  percent
    Total biodegradation:        0.45  percent
    Total sludge adsorption:    46.44  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       0.0066          1.12         1000       
   Water     11.2            900          1000       
   Soil      83.1            1.8e+003     1000       
   Sediment  5.69            8.1e+003     0          
     Persistence Time: 1.77e+003 hr