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Inherent Properties, Identifiers and References
ChemSpider ID: 337269
Empirical Formula: C19H16O4
Molecular Weight: 308.3279
Nominal Mass: 308 Da
Average Mass: 308.3279 Da
Monoisotopic Mass: 308.104859 Da
Quick Links: Permalink Similar Isomers
Systematic Name: phenethyl 5,6-dihydroxynaphthalene-2-carboxylate
SMILES: O=C(OCCc1ccccc1)c3cc2ccc(O)c(O)c2cc3
InChI: InChI=1/C19H16O4/c20-17-9-7-14-12-15(6-8-16(14)18(17)21)19(22)23-​11-10-13-4-2-1-3-5-13/h1-9,12,20-21H,10-11H2
InChIKey: OFPFJSWYCBDRHK-UHFFFAOYAT
(Details...) Original Reference(s) Filter
Data Source External ID(s)
ChemDB 4929454
DiscoveryGate 380595
DTP/NCI 666252
NIAID 085236
PubChem 380595
Thomson Pharma 00802955
(Details...) Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

.beta.-Ph​enylethyl​ 5,6-dihy​droxy-2-n​aphthoate

(Details...) Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

AIDS085236

AIDS-0852​36

NSC666252

(Details...) Predicted Properties
LogP: ACD/LogP: 4.11
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): ACD/LogD (pH 7.4):
ACD/BCF (pH 5.5): ACD/BCF (pH 7.4):
ACD/KOC (pH 5.5): ACD/KOC (pH 7.4):
#H bond acceptors: 4 #H bond donors: 2
#Freely Rotating Bonds: 7 Polar Surface Area: 44.76 Å2
Index of Refraction: 1.677 Molar Refractivity: 88.75 cm3
Molar Volume: 235.5 cm3 Polarizability: 35.18 10-24cm3
Surface Tension: 60.9 dyne/cm Density: 1.309 g/cm3
Flash Point: 198.5 °C Enthalpy of Vaporization: 84.65 kJ/mol
Boiling Point: 538.7 °C at 760 mmHg Vapour Pressure: 3.23E-12 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  4.24

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  472.20  (Adapted Stein & Brown method)
    Melting Pt (deg C):  199.61  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  5.42E-011  (Modified Grain method)
    Subcooled liquid VP: 3.76E-009 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  9.933
       log Kow used: 4.24 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  24.555 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Esters
       Phenols

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   3.93E-015  atm-m3/mole
   Group Method:   5.35E-016  atm-m3/mole
 Henrys LC [VP/WSol estimate using EPI values]:  2.214E-012 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  4.24  (KowWin est)
  Log Kaw used:  -12.794  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  17.034
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   1.1893
   Biowin2 (Non-Linear Model)     :   0.9990
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.7179  (weeks-months)
   Biowin4 (Primary Survey Model) :   3.6476  (days-weeks  )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.3429
   Biowin6 (MITI Non-Linear Model):   0.1906
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.3375
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  5.01E-007 Pa (3.76E-009 mm Hg)
  Log Koa (Koawin est  ): 17.034
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  5.98 
       Octanol/air (Koa) model:  2.65E+004 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.995 
       Mackay model           :  0.998 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant =  76.8115 E-12 cm3/molecule-sec
      Half-Life =     0.139 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     1.671 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 0.997 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  1.746E+005
      Log Koc:  5.242 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
  Total Kb for pH > 8 at 25 deg C :  4.656E-002  L/mol-sec
  Kb Half-Life at pH 8:     172.299  days   
  Kb Half-Life at pH 7:       4.717  years  

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 2.567 (BCF = 368.9)
       log Kow used: 4.24 (estimated)

 Volatilization from Water:
    Henry LC:  5.35E-016 atm-m3/mole  (estimated by Group SAR Method)
    Half-Life from Model River: 1.922E+012  hours   (8.007E+010 days)
    Half-Life from Model Lake : 2.096E+013  hours   (8.735E+011 days)

 Removal In Wastewater Treatment:
    Total removal:              42.05  percent
    Total biodegradation:        0.41  percent
    Total sludge adsorption:    41.63  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       1.18e-006       3.34         1000       
   Water     10.6            900          1000       
   Soil      85.1            1.8e+003     1000       
   Sediment  4.36            8.1e+003     0          
     Persistence Time: 1.93e+003 hr