ChemSpider 2D Image | Sorafenib tosylate | C28H24ClF3N4O6S

Sorafenib tosylate

  • Molecular FormulaC28H24ClF3N4O6S
  • Average mass637.027 Da
  • Monoisotopic mass636.105713 Da
  • ChemSpider ID359744

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 4-methylbenzenesulfonate (1:1) [ACD/Index Name]
4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methyl-2-pyridinecarboxamide 4-methylbenzenesulfonate (1:1) [ACD/IUPAC Name]
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide 4-methylbenzenesulfonate (1:1)
4-[4-({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL}AMINO)PHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE; 4-METHYLBENZENE-1-SULFONIC ACID
475207-59-1 [RN]
4-methylbenzene-1-sulfonic acid
4-Methylbenzolsulfonsäure --4-[4-({[4-chlor-3-(trifluormethyl)phenyl]carbamoyl}amino)phenoxy]-N-methyl-2-pyridincarboxamid (1:1) [German] [ACD/IUPAC Name]
4-Methylbenzolsulfonsäure--4-[4-({[4-chlor-3-(trifluormethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridin-2-carboxamid(1:1)
5T62Q3B36J
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BAY 54-9085 [DBID]
6 [DBID]
BAY 43-9006 [DBID]
NSC724772 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      PDGFR inhibitor; Raf inhibitor; FLT3 inhibitor, FGFR inhibitor, RET inhibitor; Mast/stem cell GFR Kit TargetMol T0093

    • Bio Activity:

      MAPK MedChem Express HY-10201A
      MAPK ; MedChem Express HY-10201A
      PDGFR??, B-raf, RAF-1, FLT3, Mast/stem cell GFR, FGFR1, ret;Mast/stem cell GFR Kit TargetMol T0093
      Raf MedChem Express HY-10201A
      Sorafenib tosylate (BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mut ant BRAF activity in vitro. MedChem Express
      Sorafenib tosylate (BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6 nM, 22 nM and 90 nM for Raf-1, B-Raf, and VEGFR2 respectively, BAY 43-9006 suppresses both wild-type and V599E mutant BRAF activity in vitro.; IC50 Value: 6 nM (Raf-1); 22 nM (B-Raf); 90 nM (VEGFR2) [1]; Target: Raf-1; Sorafenib is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma). MedChem Express HY-10201A
      Tyrosine Kinase/Adaptors; MAPK Signaling TargetMol T0093

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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