ChemSpider 2D Image | perindopril t-butylamine | C23H43N3O5

perindopril t-butylamine

  • Molecular FormulaC23H43N3O5
  • Average mass441.605 Da
  • Monoisotopic mass441.320282 Da
  • ChemSpider ID390073

  • defined stereocentres - 5 of 5 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

perindopril t-butylamine
(2S-(1(R*(R*)),2a,3ab,7ab))-1-(2-((1-(Ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic Acid compd. with 2-Methyl-2-propanamine (1:1)
(2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid 1-Ethyl Ester compound with tert-Butylamine (1:1)
(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indol-2-carbonsäure--2-methylpropan-2-amin(1:1)
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1)
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-2-pentanyl]amino}propanoyl]octahydro-1H-indol-2-carbonsäure --2-methyl-2-propanamin (1:1) [German] [ACD/IUPAC Name]
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-2-pentanyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methyl-2-propanamine (1:1) [ACD/IUPAC Name]
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

S-9490 [DBID]
C07707 [DBID]
CHEBI:8025 [DBID]
D00624 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      RAAS inhibitor; ACE inhibitor; MRP inhibitor;ChE inhibitor TargetMol T1484L

    • Bio Activity:

      ACE;MRP1;ChE TargetMol T1484L
      Angiogenesis;Endocrinology/ Hormones TargetMol T1484L
      Angiotensin-Converting Enzyme Tocris Bioscience 4302
      Angiotensin-converting Enzyme (ACE) MedChem Express HY-B0130A
      Angiotensin-converting enzyme (ACE) inhibitor Tocris Bioscience 4302
      Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice. Tocris Bioscience 4302
      Enzymes Tocris Bioscience 4302
      Metabolism/Protease MedChem Express HY-B0130A
      Metabolism/Protease; MedChem Express HY-B0130A
      Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease. MedChem Express
      Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.; Target: ACE; Perindopril is a long-acting ACE inhibitor. MedChem Express HY-B0130A
      Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.;Target: ACEPerindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (trade name Aceon). According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms. Perindopril is one of the most prescribed inhibitors of angiotensin converting enzyme, has a large evidence base, which allows to use it in patients wi MedChem Express HY-B0130A
      Proteases Tocris Bioscience 4302

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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