ChemSpider 2D Image | Optival | C21H27Na2O8P

Optival

  • Molecular FormulaC21H27Na2O8P
  • Average mass484.388 Da
  • Monoisotopic mass484.123901 Da
  • ChemSpider ID390145

  • Charge - Charge

    defined stereocentres - 7 of 7 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

11b,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(Disodium phosphate)
11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate)
125-02-0 [RN]
204-722-9 [EINECS]
206-120-1 [EINECS]
Codelsol
Dinatrium-(11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-ylphosphat [German] [ACD/IUPAC Name]
Dinatrium-2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethylphosphat
Disodium (11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate [ACD/IUPAC Name]
disodium (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-1-[2-(phosphonatooxy)acetyl]-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D00981 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      An organic sodium salt of prednisolone phosphate. It is an ophthalmology drug used for the treatment of short-term inflammatory eye conditions and helps relieve inflammation, redness and irritation of the eyes. ChEBI CHEBI:8379

    • Bio Activity:

      Glucocorticoid Receptor MedChem Express HY-B0645
      GPCR/G protein MedChem Express HY-B0645
      GPCR/G protein; MedChem Express HY-B0645
      Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. MedChem Express
      Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.; Target: Glucocorticoid Receptor; Prednisolone irreversibly binds with glucocortic oid receptors (GR) alpha and beta for which they have a high affinity. MedChem Express HY-B0645
      Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.;Target: Glucocorticoid ReceptorPrednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity. Prednisolone can activate and influence biochemical behaviour of most cells. The steroid/receptor complexes dimerise and interact with cellular DNA in the nucleus, binding to steroid-response elements and modifying gene transcription. They induce synthesis of some proteins, and inhibit synthesis of . Prednisolone exerted a delayed biphasic effect on the resistant CCRF-CEM leukemic cell line, necrotic at low doses and apoptotic at higher doses. At low doses, prednisolone exerted a pre-dominant mitogenic effect despite its induction on total cell death, while at higher doses, prednisolone's mitogenic and cell death effects were counterbalanced [1, 2]. MedChem Express HY-B0645

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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