ChemSpider 2D Image | Foipan mesylate | C21H26N4O8S

Foipan mesylate

  • Molecular FormulaC21H26N4O8S
  • Average mass494.518 Da
  • Monoisotopic mass494.147125 Da
  • ChemSpider ID39251

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate
4-{2-[(DIMETHYLCARBAMOYL)METHOXY]-2-OXOETHYL}PHENYL 4-[(DIAMINOMETHYLIDENE)AMINO]BENZOATE
4-{2-[2-(Dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate methanesulfonate (1:1) [ACD/IUPAC Name]
59721-29-8 [RN]
Acide méthanesulfonique - 4-carbamimidamidobenzoate de 4-{2-[2-(diméthylamino)-2-oxoéthoxy]-2-oxoéthyl}phényle (1:1) [French] [ACD/IUPAC Name]
Benzeneacetic acid, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-, 2-(dimethylamino)-2-oxoethyl ester, methanesulfonate (1:1) [ACD/Index Name]
Camostat Mesylate
Foipan mesylate
Methansulfonsäure --4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl-4-carbamimidamidobenzoat (1:1) [German] [ACD/IUPAC Name]
MFCD00941410 [MDL number]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

451M50A1EQ [DBID]
FOY 305 [DBID]
D01766 [DBID]
Foy-305 [DBID]
UNII:451M50A1EQ [DBID]
UNII-451M50A1EQ [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Sodium Channel inhibitor TargetMol T2391

    • Chemical Class:

      A methanesulfonate (mesylate) salt prepared from equimolar amounts of camostat and methanesulfonic acid. It is a serine protease inhibitor approved and marketed in Japan in 1985 for the alleviation o f acute symptoms associated with chronic pancreatitis. In 1994, it was approved for the treatment of postoperative reflux esophagitis. ChEBI CHEBI:31347

    • Bio Activity:

      <p>Serine protease inhibitor. Orally active.</p> <p>Show various biological actions including antiviral, anticancer and suppresses pancreatitis-induced pain in rats.</p> <p>Inhibits the transmembrane protease TMPRSS2 and partially blocks entry of SARS-Cov-2 into lung cells in vitro.</p> Hello Bio HB3595
      Camostat Mesylate(FOY305; FOY-S980) is a trypsin-like protease inhibitor MedChem Express
      Camostat Mesylate(FOY305; FOY-S980) is a trypsin-like protease inhibitor; Target: Trypsin-like protease; Camostat mesilate (500 mM) inhibits generation of TGF-beta by suppressing plasmin activity and reduces the activity of TGF-beta, which blocks in vitro activation of HSCs [1]. MedChem Express HY-13512
      Camostat Mesylate(FOY305; FOY-S980) is a trypsin-like protease inhibitor;Target: Trypsin-like proteaseCamostat mesilate (500 mM) inhibits generation of TGF-beta by suppressing plasmin activity and reduces the activity of TGF-beta, which blocks in vitro activation of HSCs [1]. Camostat mesilate (20 mM) combined with insulin results a significant hypoglycemic effect following large intestinal administration. Camostat mesilate (20 mM) is effective in reducing insulin degradation in both small and large intestinal homogenates of rats [2]. Camostat mesilate (2 mM) inhibits MCP-1 and TNF- production in activated rat monocytes. Camostat mesilate (2 mM) inhibits proliferation and MCP-1 production of cultured rat PSCs. Camostat mesilate (1 mg/g) prevents pancreatic atrophy and improves pancreatic exocrine function of rat chronic pancreatitis induced by DBTC. Camostat mesilate (1 mg/g) inhibits chronic inflammation and pancreatic fibrosis induced by DBTC. Camostat mesilate (1 mg/g) inhibits MedChem Express HY-13512
      Enzymes Tocris Bioscience 3193
      epithelial sodium channel (ENaC) TargetMol T2391
      Membrane Transporter/Ion Channel TargetMol T2391
      Orally active protease inhibitor Tocris Bioscience 3193
      Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral ad ministration. Tocris Bioscience 3193
      Orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Suppresses pancreatitis-induced pain in rats following oral administration. Tocris Bioscience 3193
      Other Proteases Tocris Bioscience 3193
      Others MedChem Express HY-13512
      Proteases Tocris Bioscience 3193

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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