PLANNED MAINTENANCE

There will be scheduled maintenance work beginning on Wednesday 26th February 2020 from 11:00 AM through to 12.00 PM (GMT).

During this time, you may not be able to log into ChemSpider. We apologise for any inconvenience this might cause and thank you for your patience.

Found 1 result

Search term: FDMQDKQUTRLUBU (Found by InChIKey (skeleton match))

ChemSpider 2D Image | Olmutinib | C26H26N6O2S

Olmutinib

  • Molecular FormulaC26H26N6O2S
  • Average mass486.589 Da
  • Monoisotopic mass486.183807 Da
  • ChemSpider ID45743494

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

10093
1353550-13-6 [RN]
2-Propenamide, N-[3-[[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-4-yl]oxy]phenyl]- [ACD/Index Name]
CHL9B67L95
N-{3-[(2-{[4-(4-Methyl-1-piperazinyl)phenyl]amino}thieno[3,2-d]pyrimidin-4-yl)oxy]phenyl}acrylamid [German] [ACD/IUPAC Name]
N-{3-[(2-{[4-(4-Methyl-1-piperazinyl)phenyl]amino}thieno[3,2-d]pyrimidin-4-yl)oxy]phenyl}acrylamide [ACD/IUPAC Name]
N-{3-[(2-{[4-(4-Méthyl-1-pipérazinyl)phényl]amino}thiéno[3,2-d]pyrimidin-4-yl)oxy]phényl}acrylamide [French] [ACD/IUPAC Name]
olmutinib [French] [INN]
olmutinib [Spanish] [INN]
Olmutinib [INN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BI 1482694 [DBID]
HM61713 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Btk MedChem Express HY-19730
      EGFR MedChem Express HY-19730
      JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; MedChem Express HY-19730
      Olmutinib (HM71224) is a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). MedChem Express HY-19730
      Olmutinib is an EGFR tyrosine kinase inhibitor.;Target: EGFROlmutinib is an Epidermal growth factor receptor (EGFR) antagonist. MedChem Express HY-19730
      Protein Tyrosine Kinase/RTK MedChem Express HY-19730

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.706
Molar Refractivity: 141.6±0.3 cm3
#H bond acceptors: 8
#H bond donors: 2
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 0
ACD/LogP: 4.95
ACD/LogD (pH 5.5): 1.75
ACD/BCF (pH 5.5): 3.92
ACD/KOC (pH 5.5): 23.17
ACD/LogD (pH 7.4): 3.47
ACD/BCF (pH 7.4): 204.07
ACD/KOC (pH 7.4): 1205.58
Polar Surface Area: 111 Å2
Polarizability: 56.1±0.5 10-24cm3
Surface Tension: 67.0±3.0 dyne/cm
Molar Volume: 364.1±3.0 cm3

Click to predict properties on the Chemicalize site






Advertisement