ChemSpider 2D Image | carfilzomib-d8 | C40H49D8N5O7

carfilzomib-d8

  • Molecular FormulaC40H49D8N5O7
  • Average mass727.959 Da
  • Monoisotopic mass727.476013 Da
  • ChemSpider ID45848902

  • defined stereocentres - 5 of 5 defined stereocentres

    Non-standard isotope - Non-standard isotope

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1537187-53-3 [RN]
Carfilzomib-(morpholine-d8)
carfilzomib-d8
L-Phenylalaninamide, N-[(2S)-2-[[2-(4-morpholinyl-d8)acetyl]amino]-1-oxo-4-phenylbutyl]-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]- [ACD/Index Name]
N-[(2S)-2-({2-[(2H8)-4-Morpholinyl]acétyl}amino)-4-phénylbutanoyl]-L-leucyl-N-{(2S)-4-méthyl-1-[(2R)-2-méthyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phénylalaninamide [French] [ACD/IUPAC Name]
N-[(2S)-2-{[(2H8)-4-Morpholinylacetyl]amino}-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamid [German] [ACD/IUPAC Name]
N-[(2S)-2-{[(2H8)-4-Morpholinylacetyl]amino}-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide [ACD/IUPAC Name]
(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[[2-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)acetyl]amino]-4-phenylbutanoyl]amino]pentanamide

    Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

    Density: 1.2±0.1 g/cm3
    Boiling Point: 975.6±65.0 °C at 760 mmHg
    Vapour Pressure: 0.0±0.3 mmHg at 25°C
    Enthalpy of Vaporization: 142.3±3.0 kJ/mol
    Flash Point: 543.8±34.3 °C
    Index of Refraction: 1.551
    Molar Refractivity: 197.5±0.3 cm3
    #H bond acceptors: 12
    #H bond donors: 4
    #Freely Rotating Bonds: 20
    #Rule of 5 Violations: 3
    ACD/LogP: 6.71
    ACD/LogD (pH 5.5): 4.43
    ACD/BCF (pH 5.5): 1256.10
    ACD/KOC (pH 5.5): 5186.88
    ACD/LogD (pH 7.4): 4.59
    ACD/BCF (pH 7.4): 1794.35
    ACD/KOC (pH 7.4): 7409.50
    Polar Surface Area: 158 Å2
    Polarizability: 78.3±0.5 10-24cm3
    Surface Tension: 48.0±3.0 dyne/cm
    Molar Volume: 619.6±3.0 cm3

    Click to predict properties on the Chemicalize site


    Advertisement