ChemSpider 2D Image | Amlodipine maleate | C24H29ClN2O9

Amlodipine maleate

  • Molecular FormulaC24H29ClN2O9
  • Average mass524.948 Da
  • Monoisotopic mass524.156128 Da
  • ChemSpider ID4940607

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-2-((2-Aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester (Z)-2-Butenedioate (1:1)
(2Z)-2-Butendisäure --3-ethyl-5-methyl-2-[(2-aminoethoxy)methyl]-4-(2-chlorphenyl)-6-methyl-1,4-dihydro-3,5-pyridindicarboxylat (1:1) [German] [ACD/IUPAC Name]
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (2Z)-2-butenedioate (1:1) [ACD/Index Name]
3-Ethyl 5-Methyl (±)-2-((2-Aminoethoxy)methyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate Maleate (1:1)
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate (2Z)-2-butenedioate (1:1) [ACD/IUPAC Name]
3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (2Z)-but-2-enedioate (1:1)
88150-47-4 [RN]
Acide (2Z)-2-butènedioïque - 2-[(2-aminoéthoxy)méthyl]-4-(2-chlorophényl)-6-méthyl-1,4-dihydro-3,5-pyridinedicarboxylate de 3-éthyle et de 5-méthyle (1:1) [French] [ACD/IUPAC Name]
Amlodipine (±)-form Maleate
Amlodipine maleate [USAN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

UK-48340-11 [DBID]
12WW9T2ITA [DBID]
D02914 [DBID]
UK 48,340-11 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Amlodipine maleate is a long-acting calcium channel blocker. MedChem Express
      Amlodipine maleate is a long-acting calcium channel blocker.; Target: Calcium Channel; Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. MedChem Express HY-B0317A
      Amlodipine maleate is a long-acting calcium channel blocker.;Target: Calcium ChannelAmlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. Experimental data suggest amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Negative inotropic effects, or decreased heart muscle contractility, can be detected in vitro, but such effects have not been seen in intact animals at therapeutic doses. Serum calcium concentration is not affected by amlodipine. Within the physiologic pH range, am MedChem Express HY-B0317A
      Calcium Channel MedChem Express HY-B0317A
      Membrane Tranporter/Ion Channel MedChem Express HY-B0317A
      Membrane Tranporter/Ion Channel; MedChem Express HY-B0317A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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