ChemSpider 2D Image | Cardioxane | C11H17ClN4O4

Cardioxane

  • Molecular FormulaC11H17ClN4O4
  • Average mass Da
  • Monoisotopic mass Da
  • ChemSpider ID5293431
  • defined stereocentres - 1 of 1 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1263283-43-7 [RN]
149003-01-0 [RN]
2,6-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-, hydrochloride (1:1) [ACD/Index Name]
2,6-piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-, monohydrochloride
2,6-Piperazinedione, 4-[(1S)-2-(3,5-dioxo-1-piperazinyl)-1-methylethyl]-, hydrochloride (1:1)
4,4'-(2S)-Propan-1,2-diyldipiperazin-2,6-dionhydrochlorid
4,4'-(2S)-propane-1,2-diyldipipérazine-2,6-dione chlorhydrate
4,4'-(2S)-Propane-1,2-diyldipiperazine-2,6-dione hydrochloride (1:1)
4,4'-[(2S)-1,2-Propandiyl]di(2,6-piperazindion)hydrochlorid (1:1) [German] [ACD/IUPAC Name]
4,4'-[(2S)-1,2-Propanediyl]di(2,6-piperazinedione) hydrochloride (1:1) [ACD/IUPAC Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5346058Q7S [DBID]
UNII:5346058Q7S [DBID]
ADR-529 [DBID]
ICRF-187 [DBID]
NSC-169780 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Dexrazoxane Hcl( ICRF-187 Hcl) is a cardioprotective agent. MedChem Express http://www.medchemexpress.com/I2906.html, HY-76201
      Dexrazoxane Hcl( ICRF-187 Hcl) is a cardioprotective agent. ;IC50 value:;Target: cardioprotective agentAs a derivative of EDTA, dexrazoxane chelates iron, thus reduce the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs. MedChem Express HY-76201
      DNA Topoisomerase Tocris Bioscience 3857
      Enzymes Tocris Bioscience 3857
      Isomerases Tocris Bioscience 3857
      Others MedChem Express HY-76201
      Topoisomerase II inhibitor Tocris Bioscience 3857
      Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway. Tocris Bioscience 3857
      Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway. Tocris Bioscience 3857

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site






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