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Found 1 result

Search term: NQRIKTDKFHAOKC (Found by InChIKey (skeleton match))

ChemSpider 2D Image | Pardoprunox hydrochloride | C12H16ClN3O2

Pardoprunox hydrochloride

  • Molecular FormulaC12H16ClN3O2
  • Average mass269.727 Da
  • Monoisotopic mass269.093109 Da
  • ChemSpider ID5293721

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-, hydrochloride (1:1) [ACD/Index Name]
269718-83-4 [RN]
7-(4-Methyl-1-piperazinyl)-1,3-benzoxazol-2(3H)-one hydrochloride (1:1) [ACD/IUPAC Name]
7-(4-Méthyl-1-pipérazinyl)-1,3-benzoxazol-2(3H)-one, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
7-(4-Methyl-1-piperazinyl)-1,3-benzoxazol-2(3H)-onhydrochlorid (1:1) [German] [ACD/IUPAC Name]
Pardoprunox hydrochloride [USAN]
269718-84-5 [RN]

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

DU 126891 hydrochloride [DBID]
SLV 308 hydrochloride [DBID]
SLV-308 [DBID]
SME-308 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Dopamine Receptor MedChem Express HY-14958A
      GPCR/G protein MedChem Express HY-14958A
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-14958A
      Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.; IC50 value: 8.1/8.6/8.5 (pKi, for D2/ D3/5-HT1A receptor); Target: dopamine D2 and D3 receptor, 5-HT1A receptor; in vitro: Pardoprunox also binds to D4 (pKi = 7.8), ?1-adrenergic (pKi = 7.8), ?2-adrenergic (pKi = 7.4), and 5-HT7 receptors (pKi = 7.2) with lower affinity. MedChem Express HY-14958A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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