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ChemSpider 2D Image | Atorvastatin calcium | C66H68CaF2N4O10

Atorvastatin calcium

  • Molecular FormulaC66H68CaF2N4O10
  • Average mass1155.342 Da
  • Monoisotopic mass1154.453003 Da
  • ChemSpider ID54809
  • Charge - Charge


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

134523-03-8 [RN]
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, (βR,δR)- (2:1) [ACD/Index Name]
Atorvastatin Calcium
Atorvastatin calcium [USAN]
ATORVASTATIN CALCIUM ANHYDROUS
Atorvastatin hemicalcium salt
bis{(3R,5R)-7-[2-(4-fluorophényl)-5-(1-méthyléthyl)-3-phényl-4-(phénylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate} de calcium [French]
Bis{(3R,5R)-7-[2-(4-fluorophényl)-5-isopropyl-3-phényl-4-(phénylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate} de calcium [French] [ACD/IUPAC Name]
C0GEJ5QCSO
Calcium (bR,dR)-2-(p-fluorophenyl)-b,d-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CI 981 [DBID]
DRG 0321 [DBID]
YM 548 [DBID]
CI-981 [DBID]
D00887 [DBID]
DRG-0321 [DBID]
LS-136974 [DBID]
YM-548 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      IRRITANT Matrix Scientific 097734
      Sold for research purposes under agreement from Pfizer Inc. Tocris Bioscience 3776
    • Chemical Class:

      An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio. ChEBI CHEBI:50686, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:50686
    • Bio Activity:

      Enzymes Tocris Bioscience 3776
      HMG-CoA Reductase Tocris Bioscience 3776
      Potent HMG-CoA reductase inhibitor Tocris Bioscience 3776
      Potent HMG-CoA reductase inhibitor (IC50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation i n vitro and exhibits antinociceptive effects in the inflammatory hypernociception model. Tocris Bioscience 3776
      Potent HMG-CoA reductase inhibitor (IC50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model. Tocris Bioscience 3776
      Reductases Tocris Bioscience 3776

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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