ChemSpider 2D Image | Venlafaxine hydrochloride | C17H28ClNO2

Venlafaxine hydrochloride

  • Molecular FormulaC17H28ClNO2
  • Average mass313.863 Da
  • Monoisotopic mass313.180847 Da
  • ChemSpider ID56641

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

Venlafaxine hydrochloride [INN] [JAN] [USAN]
(±)-1-(a-((Dimethylamino)methyl)-p-methoxybenzyl)cyclohexanol hydrochloride
1-[2-(diméthylamino)-1-(4-méthoxyphényl)éthyl]cyclohexanol chlorhydrate [French]
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride (1:1) [ACD/IUPAC Name]
1-[2-(Diméthylamino)-1-(4-méthoxyphényl)éthyl]cyclohexanol, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanolhydrochlorid [German]
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanolhydrochlorid (1:1) [German] [ACD/IUPAC Name]
99300-78-4 [RN]
cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, hydrochloride
Cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, hydrochloride (1:1) [ACD/Index Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D00821 [DBID]
HSDB 6699 [DBID]
LS-57096 [DBID]
PW-4112 [DBID]
Wy 45030 [DBID]
Wy-45030 [DBID]
  • Experimental Physico-chemical Properties
  • Predicted Physico-chemical Properties
  • Miscellaneous
    • Safety:

      36/37/38 LKT Labs [V1854]
      5 Axon Medchem 1727
      H303;H313;H317;H333;H334;H335;H373 Axon Medchem 1727
      H319 LKT Labs [V1854]
      no pictogram Axon Medchem 1727
      P101;P102;P103;P260;P262;P263;P264;P270;P280;P304;P312;P340 Axon Medchem 1727
      Warning Axon Medchem 1727
      Xi LKT Labs [V1854]
    • Target Organs:

      5-HT Receptor antagonist TargetMol T0472
    • Bio Activity:

      5-HT Receptor TargetMol T0472
      5-HT Transporters Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing b ehavior in the forced-swim test in rats. Tocris Bioscience 2917
      Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats. Tocris Bioscience 2917
      Neuronal Signaling MedChem Express HY-B0196A
      Neuronal Signaling; MedChem Express HY-B0196A
      Neuroscience TargetMol T0472
      Neurotransmitter Transporters Tocris Bioscience 2917
      SSRIs MedChem Express HY-B0196A
      Transporters Tocris Bioscience 2917
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. MedChem Express
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.; Target: SNRI; Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. MedChem Express HY-B0196A
      Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.;Target: SNRIVenlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. In 2007, venlafaxine was the sixth most commonly prescribed antidepressant on the U.S. retail market, with 17.2 million prescriptions.Venlafaxine is a bicyclic antidepressant, and usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotr MedChem Express HY-B0196A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site





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