ChemSpider 2D Image | Trazodone Hydrochloride | C19H23Cl2N5O

Trazodone Hydrochloride

  • Molecular FormulaC19H23Cl2N5O
  • Average mass408.325 Da
  • Monoisotopic mass407.127960 Da
  • ChemSpider ID56652

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, hydrochloride (1:?)
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, hydrochloride (1:1) [ACD/Index Name]
1,2,4-triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, monohydrochloride
2-(3-(4-(3-Chlorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one Monohydrochloride
2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one Hydrochloride
2-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo[4,3-a]pyridin-3(2H)-one Monohydrochloride
2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride
2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one hydrochloride (1:1) [ACD/IUPAC Name]
2-{3-[4-(3-Chlorophényl)-1-pipérazinyl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
2-{3-[4-(3-chlorophényl)pipérazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one chlorhydrate
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

6E8ZO8LRNM [DBID]
KB 831 [DBID]
AF 1161 [DBID]
AF-1161 [DBID]
D00820 [DBID]
EU-0101159 [DBID]
HSDB 7048 [DBID]
KB-831 [DBID]
MLS000069698 [DBID]
NSC 292811 [DBID]
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Serotonin uptake inhibitor;5-HT receptor antagonist;Adrenergic Receptor antagonist ;Histamine Receptor TargetMol T1619

    • Chemical Class:

      A hydrochloride salt prepared from equimolar amounts of trazodone and hydrogen chloride. ChEBI CHEBI:9655

    • Bio Activity:

      5-HT Receptor MedChem Express HY-B0478
      5-HT Receptors Tocris Bioscience 6336
      5-HT2 Receptors Tocris Bioscience 6336
      5-HT2A and alpha1 adrenoceptor antagonist. Enhances neuronal differentiation of mouse and human neural progenitor cells. Also inhibits PERK/eIF2alpha-P-mediated reduction in protein synthesis and restores memory deficits in a mouse dementia model. Antidepressant and neuroprotectant. Tocris Bioscience 6336
      5-HT2A and alpha1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant Tocris Bioscience 6336
      7-TM Receptors Tocris Bioscience 6336
      GPCR/G protein MedChem Express HY-B0478
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0478
      Neuroscience TargetMol T1619
      Sodium-dependent serotonin transporter;5-HT receptor;Adrenergic receptor;Histamine H1 receptor TargetMol T1619
      Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. MedChem Express
      Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.; Target: 5-HT Receptor; Trazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants. MedChem Express HY-B0478
      Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.;Target: 5-HT Receptor;Trazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants. Trazodone has been successfully used in a small number of patients with depression and pre-existing cardiovascular disease. trazodone has also been used as a hypnotic for psychotropic-induced or other insomnias with some success [1]. Trazodone is an effective hypnotic for patients with antidepressant-associated insomnia [2]. Trazodone may be helpful in men with erectile dysfunction (ED), possibly more so at higher doses, and in men with psychogenic ED. Future high-quality trials should compare trazodone with placebo and other therapies in men with depression and psychogenic ED [3]. MedChem Express HY-B0478

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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