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Inherent Properties, Identifiers and References
ChemSpider ID: 567153
Empirical Formula: C14H19NO5S
Molecular Weight: 313.3694
Nominal Mass: 313 Da
Average Mass: 313.3694 Da
Monoisotopic Mass: 313.098393 Da
Quick Links: Permalink Similar Isomers
Systematic Name: 2-[2-[(2,5-diethoxyphenyl)amino]-2-oxo-ethyl]sulfanylacetic acid
SMILES: O=C(O)CSCC(=O)Nc1cc(OCC)ccc1OCC
InChI: InChI=1/C14H19NO5S/c1-3-19-10-5-6-12(20-4-2)11(7-10)15-13(16)8-21​-9-14(17)18/h5-7H,3-4,8-9H2,1-2H3,(H,15,16)(H,17,18)
InChIKey: WCTKFHQUCXHEKP-UHFFFAOYAF
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Names and Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

[(2,5-Die​thoxy-phe​nylcarbam​oyl)-meth​ylsulfany​l]-acetic​ acid

Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Redirected by Users, Redirect Approved by Experts

(Details...) Predicted Properties
LogP: ACD/LogP: 2.73
XLogP: 1.60
# of Rule of 5 Violations: 0
ACD/LogD (pH 5.5): 0.83 ACD/LogD (pH 7.4):
ACD/BCF (pH 5.5): 1 ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 9.13 ACD/KOC (pH 7.4): 1
#H bond acceptors: 6 #H bond donors: 2
#Freely Rotating Bonds: 9 Polar Surface Area: 90.37 Å2
Index of Refraction: 1.583 Molar Refractivity: 81.97 cm3
Molar Volume: 245.1 cm3 Polarizability: 32.49 10-24cm3
Surface Tension: 51.2 dyne/cm Density: 1.278 g/cm3
Flash Point: 268 °C Enthalpy of Vaporization: 83.41 kJ/mol
Boiling Point: 519.5 °C at 760 mmHg Vapour Pressure: 1.28E-11 mmHg at 25°C
            
 Log Octanol-Water Partition Coef (SRC):
    Log Kow (KOWWIN v1.67 estimate) =  1.67

 Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
    Boiling Pt (deg C):  503.76  (Adapted Stein & Brown method)
    Melting Pt (deg C):  214.35  (Mean or Weighted MP)
    VP(mm Hg,25 deg C):  2.13E-010  (Modified Grain method)
    Subcooled liquid VP: 2.21E-008 mm Hg (25 deg C, Mod-Grain method)

 Water Solubility Estimate from Log Kow (WSKOW v1.41):
    Water Solubility at 25 deg C (mg/L):  383.3
       log Kow used: 1.67 (estimated)
       no-melting pt equation used

 Water Sol Estimate from Fragments:
    Wat Sol (v1.01 est) =  686.96 mg/L

 ECOSAR Class Program (ECOSAR v0.99h):
    Class(es) found:
       Neutral Organics-acid

 Henrys Law Constant (25 deg C) [HENRYWIN v3.10]:
   Bond Method :   3.02E-018  atm-m3/mole
   Group Method:   Incomplete
 Henrys LC [VP/WSol estimate using EPI values]:  2.291E-013 atm-m3/mole

 Log Octanol-Air Partition Coefficient (25 deg C) [KOAWIN v1.10]:
  Log Kow used:  1.67  (KowWin est)
  Log Kaw used:  -15.908  (HenryWin est)
      Log Koa (KOAWIN v1.10 estimate):  17.578
      Log Koa (experimental database):  None

 Probability of Rapid Biodegradation (BIOWIN v4.10):
   Biowin1 (Linear Model)         :   1.1450
   Biowin2 (Non-Linear Model)     :   0.9983
 Expert Survey Biodegradation Results:
   Biowin3 (Ultimate Survey Model):   2.7008  (weeks-months)
   Biowin4 (Primary Survey Model) :   4.1409  (days        )
 MITI Biodegradation Probability:
   Biowin5 (MITI Linear Model)    :   0.7013
   Biowin6 (MITI Non-Linear Model):   0.5652
 Anaerobic Biodegradation Probability:
   Biowin7 (Anaerobic Linear Model):  0.4695
 Ready Biodegradability Prediction:   NO

Hydrocarbon Biodegradation (BioHCwin v1.01):
    Structure incompatible with current estimation method!

 Sorption to aerosols (25 Dec C)[AEROWIN v1.00]:
  Vapor pressure (liquid/subcooled):  2.95E-006 Pa (2.21E-008 mm Hg)
  Log Koa (Koawin est  ): 17.578
   Kp (particle/gas partition coef. (m3/ug)):
       Mackay model           :  1.02 
       Octanol/air (Koa) model:  9.29E+004 
   Fraction sorbed to airborne particulates (phi):
       Junge-Pankow model     :  0.974 
       Mackay model           :  0.988 
       Octanol/air (Koa) model:  1 

 Atmospheric Oxidation (25 deg C) [AopWin v1.92]:
   Hydroxyl Radicals Reaction:
      OVERALL OH Rate Constant = 143.9460 E-12 cm3/molecule-sec
      Half-Life =     0.074 Days (12-hr day; 1.5E6 OH/cm3)
      Half-Life =     0.892 Hrs
   Ozone Reaction:
      No Ozone Reaction Estimation
   Reaction With Nitrate Radicals May Be Important!
   Fraction sorbed to airborne particulates (phi): 0.981 (Junge,Mackay)
    Note: the sorbed fraction may be resistant to atmospheric oxidation

 Soil Adsorption Coefficient (PCKOCWIN v1.66):
      Koc    :  22.28
      Log Koc:  1.348 

 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]:
    Rate constants can NOT be estimated for this structure!

 Bioaccumulation Estimates from Log Kow (BCFWIN v2.17):
   Log BCF from regression-based method = 0.500 (BCF = 3.162)
       log Kow used: 1.67 (estimated)

 Volatilization from Water:
    Henry LC:  3.02E-018 atm-m3/mole  (estimated by Bond SAR Method)
    Half-Life from Model River: 3.432E+014  hours   (1.43E+013 days)
    Half-Life from Model Lake : 3.744E+015  hours   (1.56E+014 days)

 Removal In Wastewater Treatment:
    Total removal:               2.03  percent
    Total biodegradation:        0.09  percent
    Total sludge adsorption:     1.94  percent
    Total to Air:                0.00  percent
      (using 10000 hr Bio P,A,S)

 Level III Fugacity Model:
           Mass Amount    Half-Life    Emissions
            (percent)        (hr)       (kg/hr)
   Air       1.88e-009       1.78         1000       
   Water     29.5            900          1000       
   Soil      70.4            1.8e+003     1000       
   Sediment  0.0832          8.1e+003     0          
     Persistence Time: 1.26e+003 hr