ChemSpider 2D Image | GNF6702 | C22H16FN7O2

GNF6702

  • Molecular FormulaC22H16FN7O2
  • Average mass429.406 Da
  • Monoisotopic mass429.134949 Da
  • ChemSpider ID58827646

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5-Oxazolecarboxamide, N-[4-fluoro-3-[6-(2-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl]-2,4-dimethyl- [ACD/Index Name]
GNF6702 [Wiki]
N-{4-Fluor-3-[6-(2-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl}-2,4-dimethyl-1,3-oxazol-5-carboxamid [German] [ACD/IUPAC Name]
N-{4-Fluoro-3-[6-(2-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl}-2,4-dimethyl-1,3-oxazole-5-carboxamide [ACD/IUPAC Name]
N-{4-Fluoro-3-[6-(2-pyridinyl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phényl}-2,4-diméthyl-1,3-oxazole-5-carboxamide [French] [ACD/IUPAC Name]
1799329-72-8 [RN]
GNF 6702
GNF-6702
MFCD31612571
N-{4-fluoro-3-[6-(pyridin-2-yl)[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]phenyl}-2,4-dimethyl-1,3-oxazole-5-carboxamide
More...
  • Miscellaneous
    • Chemical Class:

      An aromatic amide obtained by formal condensation of the carboxy group of 2,4-dimethyl-1,3-oxazole-5-carboxylic acid with the aromatic amino group of 4-fluoro-3-[6-(pyridin-2-yl)[1,2,4]triazolo[1,5-<i tal>a</ital>]pyrimidin-2-yl]aniline. A proteasome inhibitor known to be active against the three parasites that cause Chagas disease, leishmaniasis and sleeping sickness. ChEBI CHEBI:133824
      An aromatic amide obtained by formal condensation of the carboxy group of 2,4-dimethyl-1,3-oxazole-5-carboxylic acid with the aromatic amino group of 4-fluoro-3-[6-(pyridin-2-yl)[1,2,4]triazolo[1,5-a] pyrimidin-2-yl]aniline. A proteasome inhibitor known to be active against the three parasites that cause Chagas disease, leishmaniasis and sleeping sickness. ChEBI CHEBI:133824

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.5±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.733
Molar Refractivity: 115.2±0.5 cm3
#H bond acceptors: 9
#H bond donors: 1
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 0.88
ACD/LogD (pH 5.5): 1.38
ACD/BCF (pH 5.5): 6.65
ACD/KOC (pH 5.5): 135.06
ACD/LogD (pH 7.4): 1.38
ACD/BCF (pH 7.4): 6.64
ACD/KOC (pH 7.4): 134.90
Polar Surface Area: 111 Å2
Polarizability: 45.7±0.5 10-24cm3
Surface Tension: 57.5±7.0 dyne/cm
Molar Volume: 287.8±7.0 cm3

Click to predict properties on the Chemicalize site






Advertisement