ChemSpider 2D Image | Dexfenfluramine hydrochloride | C12H17ClF3N

Dexfenfluramine hydrochloride

  • Molecular FormulaC12H17ClF3N
  • Average mass267.718 Da
  • Monoisotopic mass267.100159 Da
  • ChemSpider ID59645

  • defined stereocentres - 1 of 1 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(+)-(S)-N-Ethyl-a-methyl-m-(trifluoromethyl)phenethylamine Hydrochloride
(+)-(S)-N-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine hydrochloride
(+)-Fenfluramine hydrochloride
(+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride
(2S)-N-Ethyl-1-[3-(trifluormethyl)phenyl]-2-propanaminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
(2S)-N-Ethyl-1-[3-(trifluoromethyl)phenyl]-2-propanamine hydrochloride (1:1) [ACD/IUPAC Name]
(2S)-N-Éthyl-1-[3-(trifluorométhyl)phényl]-2-propanamine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
(2S)-N-Ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride (1:1)
(S)-fenfluramine hydrochloride
(S)-N-ethyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

7114728 [DBID]
7114728; 8165762 [DBID]
8165762 [DBID]
D03713 [DBID]
DEA No. 1670 [DBID]
F112_SIGMA [DBID]
IP-001 [DBID]
S-5614 [DBID]
UN 2811 [DBID]
UN2811 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      The hydrochloride salt of (<stereo>S</stereo>)-fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike the racemate it does not possess catecholamine ago nist activity. It was formerly given by mouth in the treatment of obesity, but, like the racemate, was withdrawn wolrdwide following reports of valvular heart defects. ChEBI CHEBI:59730
      The hydrochloride salt of (S)-fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike the racemate it does not possess catecholamine ago; nist activity. It was formerly given by mouth in the treatment of obesity, but, like the racemate, was withdrawn wolrdwide following reports of valvular heart defects. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:59730
      The hydrochloride salt of (S)-fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike the racemate it does not possess catecholamine agonist activity. It was formerly given by mouth in the treatment of obesity, but, like the racemate, was withdrawn wolrdwide following reports of valvular heart defects. ChEBI CHEBI:59730

    • Bio Activity:

      5-HT re-uptake inhibitor. Also stimulates 5-HT release Tocris Bioscience 2695
      5-HT re-uptake inhibitor. Stimulates 5-HT release to indirectly agonize serotonin receptors. Shows anorectic activity. Hello Bio [HB1729]
      5-HT re-uptake inhibitor. Stimulates 5-HT release. Hello Bio [HB1729]
      5-HT Transporters Tocris Bioscience 2695
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio [HB1729]
      Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice. Tocris Bioscience 2695
      Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice. Tocris Bioscience 2695
      Neurotransmitter Transporters Tocris Bioscience 2695
      Receptors & Transporters/Transporters/5-HT uptake & transport Hello Bio [HB1729]
      Transporters Tocris Bioscience 2695

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


Advertisement