ChemSpider 2D Image | Lidocaine hydrochloride | C14H23ClN2O

Lidocaine hydrochloride

  • Molecular FormulaC14H23ClN2O
  • Average mass270.798 Da
  • Monoisotopic mass270.149902 Da
  • ChemSpider ID6075

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(Diethylamino)-2',6'-acetoxylidide Monohydrochloride
2-(diéthylamino)-N-(2,6-diméthylphényl)acétamide chlorhydrate
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide, hydrochloride (1:1)
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamidhydrochlorid
2',6'-Acetoxylidide, 2-(diethylamino)-, monohydrochloride (8CI)
200-803-8 [EINECS]
2N2&1VMR B1 F1 &&HCl [WLN]
73-78-9 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D02086 [DBID]
EU-0100669 [DBID]
L5647_SIGMA [DBID]
MLS000069665 [DBID]
Prestwick_296 [DBID]
S 202 [DBID]
SMR000058468 [DBID]
V 262 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Sodium Channel inhibitor TargetMol T1144

    • Chemical Class:

      The anhydrous form of the hydrochloride salt of lidocaine. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:50512, CHEBI:50512

    • Bio Activity:

      Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (I CAM-1), and reduction of neutrophils influx. MedChem Express
      Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.; Target: ; Lidocaine is a common local anesthetic and antiarrhythmic drug. MedChem Express HY-B0185A
      Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.;Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide?type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less MedChem Express HY-B0185A
      Membrane Transporter/Ion Channel TargetMol T1144
      Others MedChem Express HY-B0185A
      Sodium Channel TargetMol T1144

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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