ChemSpider 2D Image | amezinium metilsulfate | C12H15N3O5S

amezinium metilsulfate

  • Molecular FormulaC12H15N3O5S
  • Average mass313.330 Da
  • Monoisotopic mass313.073242 Da
  • ChemSpider ID64937

More details:

Featured data source

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

250-248-0 [EINECS]
30578-37-1 [RN]
4-Amino-6-methoxy-1-phenylpyridazin-1-ium methyl sulfate [ACD/IUPAC Name]
4-Amino-6-methoxy-1-phenylpyridazin-1-iummethylsulfat [German] [ACD/IUPAC Name]
amezinii metilsulfas [Latin] [INN]
amezinium metilsulfate [INN]
métilsulfate d'amézinium [French] [INN]
metilsulfato de amezinio [Spanish] [INN]

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D01304 [DBID]
LU 1631 [DBID]
LU-1631 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Adrenergic Receptor MedChem Express HY-A0275
      Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. ;Target: alpha and beta-1 receptorsAmezinium metilsulfate is a sympathomimetic drug used for the treatment of low blood pressure. Cardiovascular effects of the new sympathomimetic Amezinium metilsulphate are investigated in 25 patients compared with a control group (n = 25). During spinal/epidural anaesthesia 5 mg amezinium is given i.v. if blood pressure dropped greater than 20 mmHg. from starting-point. A significant recovery of blood pressure (epidural anaesthesia: syst 21%, diast 9%; spinal anaesthesia: syst 13%, diast 6.6%) and a decrease in heart rate (6.8% resp. 4,5%) are thought due to peripheral vasoconstriction. Amezinium proves a stimulating drug for alpha- and beta 1-receptors by stabilising the systemic blood pressure in spinal/epidural anaesthesia. MedChem Express HY-A0275
      GPCR/G protein; MedChem Express HY-A0275

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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