ChemSpider 2D Image | Oxaliplatin | C8H14N2O4Pt

Oxaliplatin

  • Molecular FormulaC8H14N2O4Pt
  • Average mass397.292 Da
  • Monoisotopic mass397.060150 Da
  • ChemSpider ID8062727
  • Charge - Charge

    defined stereocentres - 2 of 2 defined stereocentres


More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[Ethanedioato(2-)-κ2O1,O2]platinum - (1R,2R)-cyclohexane-1,2-diamine (1:1)
6012
61825-94-3 [RN]
Oxalate de platine(2+) (1R,2R)-1,2-cyclohexanediamine (1:1:1) [French] [ACD/IUPAC Name]
Oxaliplatin [Wiki]
Platin(2+)ethandioat-(1R,2R)-1,2-cyclohexandiamin (1:1:1) [German] [ACD/IUPAC Name]
Platinum(2+) ethanedioate - (1R,2R)-1,2-cyclohexanediamine (1:1)
Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1)
Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1) [ACD/IUPAC Name]
platinum, [ethanedioato(2-)-κO1,κO2]-, compd. with (1R,2R)-1,2-cyclohexanediamine (1:1) [ACD/Index Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

04ZR38536J [DBID]
D01790 [DBID]
UNII:04ZR38536J [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      IRRITANT Matrix Scientific 076034
    • Bio Activity:

      Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than ana log cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance. Tocris Bioscience 2623
      Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance. Tocris Bioscience 2623
      Apoptosis Tocris Bioscience 2623
      Apoptosis Inducers Tocris Bioscience 2623
      Cell Biology Tocris Bioscience 2623
      Cell Cycle/DNA Damage; MedChem Express HY-17371
      DNA alkylator/crosslinker MedChem Express HY-17371
      DNA cross-linking antitumor agent Tocris Bioscience 2623
      Oxaliplatin inhibits DNA synthesis by conforming DNA adducts. MedChem Express

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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