ChemSpider 2D Image | umifenovir hydrochloride | C22H26BrClN2O3S

umifenovir hydrochloride

  • Molecular FormulaC22H26BrClN2O3S
  • Average mass513.875 Da
  • Monoisotopic mass512.053589 Da
  • ChemSpider ID8133712

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

131707-23-8 [RN]
1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1) [ACD/Index Name]
6-Bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylic Acid Ethyl Ester Moonohydrochloride
6-Bromo-4-[(diméthylamino)méthyl]-5-hydroxy-1-méthyl-2-[(phénylsulfanyl)méthyl]-1H-indole-3-carboxylate d'éthyle, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
Arbidol HCl
Arbidol Hydrochloride
Ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate hydrochloride (1:1) [ACD/IUPAC Name]
Ethyl-6-brom-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indol-3-carboxylathydrochlorid (1:1) [German] [ACD/IUPAC Name]
umifenovir hydrochloride [INN]
(3S,4R,5R)-tetrahydro-2H-pyran-2,2,3,4,5-pentaol hydrochloride
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  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      IRRITANT Matrix Scientific 092967
    • Bio Activity:

      Anti-infection MedChem Express HY-14904A
      Anti-infection; MedChem Express HY-14904A
      Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane MedChem Express
      Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane; IC50 value:; Target: Antiviral; Anti-influenza agent; in vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.However, arbidol showed selective antiviral activity against AdV-7, a DNA virus, only when added after infection (therapeutic index (TI) = 5.5) [1]. MedChem Express HY-14904A
      Arbidol (Umifenovir) hydrochloride is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane;IC50 value:;Target: Antiviral; Anti-influenza agent;In vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.However, arbidol showed selective antiviral activity against AdV-7, a DNA virus, only when added after infection (therapeutic index (TI) = 5.5) [1]. Arb interacts with the polar head-group of phospholipid at the membrane interface. Fluorescence studies of interactions between Arb and either tryptophan derivatives or membrane peptides reconstituted into liposomes show that Arb interacts with tryptophan in the micromolar range. Interestingly, apparent binding affinities between l MedChem Express HY-14904A
      Influenza Virus MedChem Express HY-14904A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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