ChemSpider 2D Image | MFCD09027942 | C23H33ClN6O4S

MFCD09027942

  • Molecular FormulaC23H33ClN6O4S
  • Average mass525.064 Da
  • Monoisotopic mass524.197266 Da
  • ChemSpider ID8318471

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-((3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine Hydrochloride
1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine hydrochloride trihydrate
2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1) [ACD/IUPAC Name]
2-{2-Éthoxy-5-[(4-éthyl-1-pipérazinyl)sulfonyl]phényl}-5-méthyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-onhydrochlorid (1:1) [German] [ACD/IUPAC Name]
2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propyl-3H,4H-imidazo[4,3-f][1,2,4]triazin-4-one hydrochloride
2-{2-éthoxy-5-[(4-éthylpipérazin-1-yl)sulfonyl]phényl}-5-méthyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one chlorhydrate
2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride
2-{2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-onhydrochlorid
224785-91-5 [RN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

IF61NL91H3 [DBID]
UNII:IF61NL91H3 [DBID]
UNII-IF61NL91H3 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Metabolic Enzyme/Protease; MedChem Express HY-B0442A
      Others MedChem Express HY-B0442A
      PDE MedChem Express HY-B0442A
      Vardenafil Hcl is a PDE5 inhibitor used for treating erectile dysfunction. MedChem Express
      Vardenafil Hcl is a PDE5 inhibitor used for treating erectile dysfunction.; Target: PDE5; Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5 with an IC50 of 0.7 nM (6.6 nM). MedChem Express HY-B0442A
      Vardenafil Hcl is a PDE5 inhibitor used for treating erectile dysfunction.;Target: PDE5Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5 with an IC50 of 0.7 nM (6.6 nM). In contrast, the IC50 of vardenafil for PDE1 was 180 nM; for PDE6, 11 nM; for PDE2, PDE3 and PDE4, more than 1000 nM. Relative to PDE5, the ratios of the IC50 for PDE1 were 257 (60), for PDE6 16 (7.4). Vardenafil significantly enhanced the SNP-induced relaxation of human trabecular smooth muscle at 3 nM (10 nM). Vardenafil also significantly potentiated both ACh-induced and transmural electrical stimulation-induced relaxation of trabecular smooth muscle [1]. Both vardenafil doses(10 mg or 20 mg) significantly enhanced the MedChem Express HY-B0442A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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