ChemSpider 2D Image | Argatroban | C23H38N6O6S

Argatroban

  • Molecular FormulaC23H38N6O6S
  • Average mass526.649 Da
  • Monoisotopic mass526.257324 Da
  • ChemSpider ID83701
  • defined stereocentres - 3 of 4 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2R,4R)-4-Methyl-1-{N2-[(3-methyl-1,2,3,4-tetrahydro-8-chinolinyl)sulfonyl]-L-arginyl}-2-piperidincarbonsäurehydrat (1:1) [German] [ACD/IUPAC Name]
(2R,4R)-4-Methyl-1-{N2-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl}-2-piperidinecarboxylic acid hydrate (1:1) [ACD/IUPAC Name]
2-Piperidinecarboxylic acid, 1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-, (2R,4R)-, hydrate (1:1) [ACD/Index Name]
Acide (2R,4R)-4-méthyl-1-{N2-[(3-méthyl-1,2,3,4-tétrahydro-8-quinoléinyl)sulfonyl]-L-arginyl}-2-pipéridinecarboxylique, hydrate (1:1) [French] [ACD/IUPAC Name]
Argatroban [INN] [JAN] [Wiki]
(2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-pi
(2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
(2R,4R)-1-[5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid hydrate
[141396-28-3]
141396-28-3 [RN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

DK-7419 [DBID]
MCI-9038 [DBID]
MD-805 [DBID]
MDI-805 [DBID]
OM-805 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Argatroban monohydrate is a direct, selective thrombin inhibitor. MedChem Express
      Argatroban monohydrate is a direct, selective thrombin inhibitor.; Target: Thrombin; Argatroban may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. MedChem Express HY-B0375A
      Argatroban monohydrate is a direct, selective thrombin inhibitor.;Target: ThrombinArgatroban may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of argatroban is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries [1]. Argatroban, as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban [2]. MedChem Express HY-B0375A
      Metabolism/Protease MedChem Express HY-B0375A
      Metabolism/Protease; MedChem Express HY-B0375A
      Thrombin MedChem Express HY-B0375A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site





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