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ChemSpider 2D Image | QT2275000 | C8H14BrNO2

QT2275000

  • Molecular FormulaC8H14BrNO2
  • Average mass236.106 Da
  • Monoisotopic mass235.020782 Da
  • ChemSpider ID8942

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Methyl Ester Hydrobromide
1-Méthyl-1,2,5,6-tétrahydro-3-pyridinecarboxylate de méthyle bromhydrate
1-Méthyl-1,2,5,6-tétrahydro-3-pyridinecarboxylate de méthyle, bromhydrate (1:1) [French] [ACD/IUPAC Name]
1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide
206-087-3 [EINECS]
24S79B9CX7
300-08-3 [RN]
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (1:1) [ACD/Index Name]
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (9CI)
Arecaidine methyl ester hydrobromide
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

10980_FLUKA [DBID]
46063_RIEDEL [DBID]
CCRIS 4693 [DBID]
EU-0100049 [DBID]
MLS000028840 [DBID]
NSC 31750 [DBID]
Prestwick_958 [DBID]
SMR000058258 [DBID]
  • Experimental Physico-chemical Properties
  • Predicted Physico-chemical Properties
  • Miscellaneous
    • Appearance:

      Not Available Novochemy [NC-35688]
    • Safety:

      20/21/22 Novochemy [NC-35688]
      20/21/36/37/39 Novochemy [NC-35688]
      GHS07 Biosynth Q-100382
      GHS07; GHS09 Novochemy [NC-35688]
      H302 Biosynth Q-100382
      H332; H403 Novochemy [NC-35688]
      IRRITANT Matrix Scientific 083401
      P102; P210; P262; P270; P302+P352; P308+P313 Novochemy [NC-35688]
      P301+P312; P330 Biosynth Q-100382
      R52/53 Novochemy [NC-35688]
      Toxic/Light Sensitive/Store under Argon SynQuest 4H56-9-Z4, 62335
      Warning Biosynth Q-100382
      Warning Novochemy [NC-35688]
    • Target Organs:

      AChR antagonist TargetMol T2198
    • Compound Source:

      betel nuts (Arica catechu) Microsource [01500680]
    • Bio Activity:

      Arecoline Hydrobromide is a muscarinic acetylcholine receptor agonist. MedChem Express http://www.medchemexpress.com/Hygromycin-B.html, HY-B0489
      Arecoline Hydrobromide is a muscarinic acetylcholine receptor agonist. ;Target: mAChRArecoline is an alkaloid found in the areca nut. Arecoline. a drug obtained from the Areca Catechu L., induced a dose-dependent antinociception (0.3-1 mg kg(-1) i.p.) which was prevented by the muscarinic antagonists pirenzepine (0.1 microg per mouse i.c.v.) and S-(-)-ET-126 (0.01 microg per mouse i.c.v.) [1]. Arecoline exerts its excitatory actions by binding to M2-muscarinic receptors on the cell membrane of neurons of the locus coeruleus [2]. Arecoline (1 nM - 1 microM) produced a concentration-dependent contraction in both the longitudinal and the circular smooth muscle of rabbit colon. Atropine (10 microM) abolished the arecoline (80 nM)--induced contraction. M3 receptor antagonist, 4 - DAMP (0.4 microM), abolished the arecoline (80 nM)--related response, whereas M2 receptor antagonist, gallamine (0.4 microM), did not affect the effect of arecoline. These results suggest that arecoline excites MedChem Express HY-B0489
      GPCR/G protein MedChem Express HY-B0489
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0489
      mAChR MedChem Express HY-B0489
      Muscarinic AChR TargetMol T2198
      Neuroscience TargetMol T2198

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site






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